Combined treatment method for type 2 diabetes by using camel milk and rosiglitazone maleate

A technology of rosiglitazone maleate and combined therapy, which is applied in the field of medicines for the treatment of diabetes, can solve the problems of secondary failure, hypertrophy, blurred vision and the like, and achieves the effects of remarkable curative effect, convenient use and low economic burden on patients.

Inactive Publication Date: 2007-08-15
甘肃省华龙农业开发总公司
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AI Technical Summary

Problems solved by technology

[0004] It has been reported that the use of camel milk in type 1 diabetes patients can reduce the amount of insulin in patients, but there is no experimental study of camel milk on type 2 diabetes
In addition, various hypoglycemic drugs currently used clinically have contraindi

Method used

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Experimental program
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Effect test

Embodiment Construction

[0016] The present invention will be further described by following implementation now.

[0017] 1, the animal experiment of the present invention

[0018] In this study, high-fat feed method was used to prepare animal models of diabetes, and the hypoglycemic effect of camel milk was studied preliminarily, so as to provide experimental basis for future development and utilization.

[0019] 1.1 Evaluation products and positive drugs

[0020] Camel milk, rosiglitazone maleate (4mg / tablet, GlaxoSmithKline, product batch number: 06070106)

[0021] 1.2 Experimental animals

[0022] Sixty healthy 6-week-old wister female rats with a body mass of 180-200 g were selected (purchased from the Experimental Animal Center of Lanzhou University, animal qualification certificate number: GANYIDONGZI 14-006). Free to eat and drink, circadian rhythm 12 hours. Drink fresh tap water, rinse the water bottle and change the water every day. The standard common feed (purchased from the Experiment...

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PUM

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Abstract

The invention is to use camel milk and rosiglitazone maleate for combined treatment of type II diabetes, and relates to the field of medicine. It was reported that camel milk can reduce trypsin dosage for patients with type I diabetes mellitus. But there is no report about the effect of camel milk on type II diabetes. The experiment of the invention indicates that drinking camel milk alone has the same effect with rosiglitazone maleate in reducing blood sugar, blood lipid, and trypsin. Combined drinking of rosiglitazone maleate 4mg and camel milk 8ml once each day has better therapeutic effect than exclusive use of rosiglitazone maleate in reducing blood sugar, blood lipid, and trypsin. The invention has the advantages of convenient administration and low cost, and also is benefit for the economical development of pastoral zone.

Description

technical field [0001] The invention relates to the field of medicine, especially medicine for treating diabetes. Background technique [0002] Diabetes is a systemic chronic metabolic disease. It is mainly due to the absolute or relative deficiency of insulin in the body, which leads to the metabolic disorder of sugar, fat and protein. Studies have now confirmed that the main pathophysiological basis of type II diabetes is insulin resistance, that is, the body's normal response to insulin is reduced, resulting in blood insulin levels much higher than normal, which is caused by the disorder of lipid metabolism in the patient's body . Therefore, the current treatment of type II diabetes is mainly to regulate lipid metabolism, rather than simply lowering blood sugar. [0003] In today's world, with the development of economy and the prolongation of human life span, the number of diabetic patients is increasing day by day. At present, the prevalence rate in developed countri...

Claims

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Application Information

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IPC IPC(8): A61K35/20A61K9/10A61P3/10A61K31/4439
Inventor 王曙阳梁剑平宋楠楠邵伍军魏恒华兰英
Owner 甘肃省华龙农业开发总公司
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