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Traditional Chinese medicine for treating senile dementia and preparation process thereof

A traditional Chinese medicine preparation, a technology for the aged, applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, etc., which can solve the problems of large side effects and high prices.

Inactive Publication Date: 2007-09-19
天津中医药大学第一附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine is mainly symptomatic treatment, which is expensive and has many side effects

Method used

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  • Traditional Chinese medicine for treating senile dementia and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0221] In terms of 10g per weight part, take Polygonatum 9-20 parts by weight, Polygonum multiflorum 6-15 parts by weight, Angelica sinensis 6-15 parts by weight, Rehmannia glutinosa or Rehmannia glutinosa 9-20 parts by weight, Perrin 3-15 parts by weight, Amomum 3 -10 parts by weight. The combinations of the above six flavors within the weight range are all effective.

[0222] Extract the angelica plus ethanol twice, each time for 1 hour, filter, combine the extracts, recover the ethanol until there is no alcohol smell, and use the extracts for later use. Combine the dregs of Angelica sinensis with Polygonatum and Rhizoma Rhizoma Rhizoma Rhizoma Polygonatum, and Radix Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma Rhizoma, decoct twice for 1 hour each time, filter, combine the decoction, and concentrate until the active ingredient content is 1g / ml (sampling heating, water Weigh after evaporation, the same below), let stand to room temperature, add ethanol to 50% alc...

Embodiment 2

[0224] The fine powder that obtains by each component of embodiment 1 weight part and method and precipitate fine powder are evenly mixed and packed into capsules and made into capsules, and each capsule contains mixed fine powder 0.5g, oral dose, 2 times / day, 4-6 capsules / time.

Embodiment 3

[0226] After uniformly mixing the fine powder obtained by the components and the method in Example 1 by weight with the sediment fine powder, adding an appropriate amount of excipients according to the conventional method, pressing into tablets, and coating with sugar to obtain tablets. Each tablet contains 0.3g mixed fine powder, oral dose, 2 times / day, 5-10 tablets / time.

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Abstract

The invention relates to a chinese medicine preparation for senile dementia and preparation method thereof. The said preparation is composed of Polygonatum cyrtonema Hua 9-20, Radix Polygoni Multiflori 6-15, angelica sinensis 6-15, radix rehmanniae or raw radix rehmanniae 9-20, Eupatorium fortunei Turcz 3-15, Amomum villosum 3-10 by weight ratio. The method comprises the following steps in turn, ethanol extraction of partly raw material; decoction of gruffs and partly raw material; isolation of supernatant; alcohol extraction after concentration; dissolution of precipitates in distilled water; alcohol extraction; isolation of supernatant; alcohol extraction, crushing the dried precipitates into precipitates power; incorporating all the extraction liquid; crushing into precipitates power after drying; incorporating all power to produce granule, capsule and tablet by conventional method. The said chinese medicine preparation can safely and effectivelycure senile dementia and vascular dementia, especially, the intelligence curative effect, changes of MMSE individual scores, disposing capacity effect and effect of syndrome of traditional chinese medicine are all superior to the control group.

Description

technical field [0001] The invention belongs to traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation for treating senile dementia and a preparation method thereof. Background technique [0002] With the aging of the population and the extension of human life expectancy, senile dementia has become the fourth cause of death after cardiovascular and cerebrovascular diseases and tumors, among which senile dementia and vascular dementia are the two most important types. [0003] Senile dementia (Alzheimer Disease, AD) is the most common type of senile dementia, accounting for about 2 / 3 of dementia patients. As my country enters an aging society, the incidence of AD is also increasing year by year, seriously endangering the elderly. Human health, which affects the quality of life of the elderly, has constituted a major problem to be solved in life sciences. It is not only a serious public health problem, but also a severe social pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61K9/16A61K9/20A61K9/48A61P25/28
Inventor 韩景献
Owner 天津中医药大学第一附属医院
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