Topical compositions and methods for epithelial-related conditions

Abstract

The present invention relates to pharmaceutical, cosmetic and cosmeceutical topical compositions containing polyisoprenyl-protein inhibitor compounds and methods useful in the promotion of healthy epithelium and the treatment of epithelial-related conditions.

Description

[0001] Cross References to Related Applications [0001] This application claims the benefit of priority to US Provisional Application No. 60 / 579,093, filed June 12,2004. This application also claims the benefit of priority to US Provisional Patent Application Serial No. 60 / 652,921, filed February 14,2005. The entire disclosures of US Provisional Patent Application No. 60 / 597,093 and US Provisional Patent Application No. 60 / 652,921 are incorporated herein by reference. field of invention [0002] The present invention relates to pharmaceutical, cosmetic and cosmeceutical topical compositions comprising polyprenyl-protein inhibitor compounds, and methods for promoting healthy epithelium and treating epithelial-related disorders. Background of the invention [0003] Many conditions or diseases of the skin or mucous membranes are caused by inflammation caused by, inter alia, bacteria, fungi, viruses, parasites, au...

AI Technical Summary

Problems solved by technology

Unfortunately, AFC requires high concentrations to be effective, and is expected to cause generalized systemic effects and multiple side effects, as it interferes with central cellular regulatory mechanisms that typically appear to hamper its in vivo application

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