Method of removing leukocyte

一种白血球、血液的技术，应用在分离方法、化学仪器和方法、滤血等方向，达到缩短过滤时间、降低血液回收不良的效果
CN101098704AInactive Publication Date: 2008-01-02ASAHI KASEI MEDICAL CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ASAHI KASEI MEDICAL CO LTD
Publication Date
2008-01-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

A method of removing leukocytes that through reducing of clogging of a leukocyte removing filter element by blood cell components and plasma proteins being a problem encountered at the time of removing leukocytes from blood, shortens the filtration time at refrigerated filtration and exhibits high leukocyte removing performance at room temperature filtration. There is provided a method of removing leukocytes including filtering blood containing leukocytes through a leukocyte removing filter apparatus having multiple fibrous filter elements with different average fiber diameters to thereby remove leukocytes from the blood, characterized in that use is made of a leukocyte removing filter apparatus wherein the multiple fibrous filter elements include at least leukocyte removing filter element (A) of 2.0 to <4.0 [mu]m average fiber diameter and leukocyte removing filter element (B) of 0.7 to 1.2 [mu]m average fiber diameter and wherein the filter element (B) is disposed downstream of the filter element (A), the leukocyte removing filter element (B) having an average fiber diameter of >17.5% to <50% of that of the filter element (A).
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Description

technical field

[0001] The present invention relates to a leukocyte removal filter and a leukocyte removal method for removing fine aggregates and leukocytes or leukocytes and platelets in blood. More particularly, the present invention relates to a leukocyte removal filter and a leukocyte removal method for removing microscopic aggregates and leukocytes that may cause side effects of transfusion in whole blood products, red blood cell products, platelet products, plasma products, etc. for blood transfusion. In particular, the present invention relates to a leukocyte removal filter and a leukocyte removal method that exhibit excellent filtration performance under both room temperature filtration and refrigerated filtration. Background technique

[0002] In recent years, in the field of blood transfusion, a leukocyte-removed blood transfusion method in which leukocytes are removed from a blood product and then a leukocyte-depleted blood product is transfused has been widely u...

Claims

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