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Medicinal preparation for preventing tumor

A technology of anti-tumor drugs and preparations, applied in the field of medicine, can solve the problems of not enhancing the side effects of cisplatin and enhancing the cytotoxicity of pingyangmycin

Inactive Publication Date: 2008-03-26
BEIJING HOPE HUGE PHARM SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, CXL can also selectively enhance the cytotoxic effect of Pingyangmycin, play a synergistic effect on Pingyangmycin’s inhibition of human nasopharyngeal carcinoma cell proliferation, and also have a selective synergistic effect on 5-fluorouracil killing cells; And it can selectively enhance the cytotoxicity of cisplatin through the effect modification mechanism, but it does not enhance the side effect of cisplatin to inhibit bone marrow hematopoiesis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 capsule (5000 grains)

[0027] Prescription: Solanum solanum 1875g coix seed 1875g trichosanthum powder 1875g comfrey root 1875g mountain bean root 3750g half branch lotus 3750g Baiying 1875g forsythia 1875g astragalus 1875g salvia miltiorrhiza 1250g licorice 625g

[0028] 1. Weigh the above 11 herbs according to the prescription amount, add 8 to 12 times the amount of water, decoct twice for 60 to 120 minutes each time, let cool, let stand overnight, filter, combine the filtrates, and concentrate to obtain liquid A ,spare;

[0029] 2. Add 95% ethanol to liquid A to make the alcohol content reach 75%, let stand overnight, pour out the supernatant, recover ethanol, concentrate it to obtain liquid B, and set aside;

[0030] 3. Mix liquid B with appropriate amount of auxiliary materials, make granules, put them into capsules, and make 5000 granules.

Embodiment 2

[0031] Embodiment 2 capsules (50000 grains)

[0032] Prescription: Solanum solanum 18750g coix seed 18750g trichosanthum powder 18750g comfrey root 18750g mountain bean root 37500g half branch lotus 37500g Baiying 18750g forsythia 18750g astragalus 18750g salvia miltiorrhiza 12500g licorice 6250g

[0033] 1. Weigh the above 11 herbs according to the prescription amount, add 8 to 12 times the amount of water, decoct twice for 60 to 120 minutes each time, let cool, let stand overnight, filter, combine the filtrates, and concentrate to obtain liquid A ,spare;

[0034] 2. Add 95% ethanol to liquid A to make the alcohol content reach 75%, let stand overnight, pour out the supernatant, recover ethanol, concentrate it to obtain liquid B, and set aside;

[0035] 3. Mix liquid B with appropriate amount of auxiliary materials, make granules, put them into capsules, and make 50,000 granules.

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Abstract

The present invention discloses a Chinese medicine preparation for resisting tumor. It is characterized by that said Chinese medicine preparation is made up by using 11 Chinese medicinal materials of black nightshade, coix seed, puccoon, saliva root, climbing night shade, trichosanthes root and others through a certain preparation process.

Description

technical field [0001] The invention relates to an antitumor drug preparation and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] According to the 1997 report of the World Health Organization, in 1996, among the 5.8 billion people in the world, about 6.3 million people died of cancer, accounting for about 12% of the total number of deaths, of which nearly 60% died of lung cancer, gastric cancer, breast cancer, colon cancer, oral cavity cancer, etc. Cancer of the liver, liver, cervix and esophagus are the second leading causes of death after cardiovascular disease. Since 1996, more than 10.3 million cancer patients have been newly diagnosed every year in the world. By the end of 1999, the total number of cancer patients in the world has exceeded 40 million. The World Health Organization reported in 2001 that the incidence and mortality of cancer in the world increased by 22% compared with 1990, and will increase by ab...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P35/00
Inventor 王翰斌李玉娟
Owner BEIJING HOPE HUGE PHARM SCI
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