Method of preparing anticold grain based on ultrasound wave auxiliary extraction technology

Abstract

The invention relates to a novel technology for extracting the effective component of the traditional Chinese medicine and concretely relates to a novel technical method of ultrasonic extraction, which is to high efficiently extract the effective component of paeoniflorin form the compound traditional Chinese medicines of a honeysuckle, a red peony root and a male fern rhizome. The method adopts the design scheme of orthogonal experiment to obtain the dry honeysuckle, red peony root and male fern rhizome with the weight ratio of 3 to 3 to 1 by the filtration and ultrasonic extraction process based on the technical parameters of the ultrasonic intensity, the ultrasonic acting time and acting manner, the solvent type, the system temperature, the mixing manner etc., and the dry honeysuckle, red peony root and male fern rhizome are crushed and sieved (0.45 microns) as the material to be mixed with water, and the material-liquid volume ratio is 1 to 5 to 7. The ultrasonic power is 100W; the ultrasonic frequency is 25kHz; the ultrasonic acting manner is a separate excitation type ultrasonic vocalization device and a columnar radial-vibration transducer; the ultrasonic acting time is 40 minutes; the extraction temperature is 45 DEG C; the mixing manner is the gas lift-type mixing. The extracted liquid is filtered and condensed for the comparative consistency of 1.08 to 1.16, and ethanol is added till the alcohol content is 50 percent, and the liquid is mixed uniformly to be aged overnight and filtered; the filtrate is regenerated the ethanol and condensed; medical powder granules are obtained by spraying and drying at the extract flow velocity of 4 to 6 ml / min and the atomizing pressure of 1 to 2 kg. According to the method, the yield of the medical powder granular matter is 32 percent; the content of the paeoniflorin is 5.92 percent.

Description

1. Technical field [0001] The invention relates to a new technology for extracting effective components of traditional Chinese medicines, in particular to a new ultrasonic extraction process for efficiently extracting effective components paeoniflorin from compound traditional Chinese medicines honeysuckle, red peony root and cotton horse root. 2. Background technology [0002] The chemical meaning of extraction is to use a suitable solvent and an appropriate method to leach the required components from the sample material as completely as possible, avoiding or reducing the introduction of harmful components or other impurities. Extracting chemical components from plants for medicinal purposes has a history of nearly 5,000 years in the traditional medicine of the motherland. Traditional extraction methods can be divided into two categories according to the different energy requirements of the extraction process. One is the heating extraction method, which mainly includes di...

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Problems solved by technology

Among them, the yield of particulate matter is about 25%, and the highest content of paeoniflorin is 4.52%. The active ingredients in some raw materials are destroyed during the high-temperature extraction process, which affects the extraction efficiency and drug quality.

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