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Application of plant sterol in preparing medicine for treating chronic non-bacterial prostatitis

A phytosterol, non-bacterial technology, applied in the preparation of a drug for the treatment of chronic non-bacterial prostatitis, in the field of pharmaceutical compositions prepared from phytosterol, can solve the problems of low cure rate, many adverse reactions, poor treatment effect and the like

Inactive Publication Date: 2008-04-30
上海药谷药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the drugs commonly used in the treatment of chronic non-bacterial prostate include antibiotics, anti-inflammatory drugs, α-receptor blockers, herbal medicines, immunosuppressants and other drugs. The existing therapeutic drugs have poor therapeutic effect, low cure rate, The defect of many adverse reactions, so the clinical application is limited
The above-mentioned literature reports on the properties, functions and applications of phytosterols, but does not involve its description in the treatment of chronic non-bacterial prostatitis

Method used

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  • Application of plant sterol in preparing medicine for treating chronic non-bacterial prostatitis
  • Application of plant sterol in preparing medicine for treating chronic non-bacterial prostatitis
  • Application of plant sterol in preparing medicine for treating chronic non-bacterial prostatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0168] Preparation of Phytosterol Ordinary Capsules

[0169] Prescription: Phytosterols 40mg

[0170] Lactose 155mg

[0171] Carboxymethyl Starch Sodium 5mg

[0172] 5% povidone (K30) in 70% ethanol solution

[0173] Take phytosterol, lactose, sodium carboxymethyl starch through a 80-mesh sieve and mix evenly, add 5% povidone K30 in 70% ethanol solution in an appropriate amount to make a soft material, pass through a 40-mesh sieve to granulate. 50-60 ℃ oven blast drying. The dry granules are sieved through a 40-mesh sieve. Fill No. 1 capsules according to the prescription, and each capsule contains 40 mg of phytosterol.

Embodiment 2

[0175] Preparation of Phytosterol Ordinary Capsules

[0176] Prescription: Phytosterols 40mg

[0177] Microcrystalline Cellulose 155mg

[0178] Crospovidone 5mg

[0179] 5% povidone (K30) in 70% ethanol solution

[0180] Take phytosterol, microcrystalline cellulose, and cross-linked povidone through a 80-mesh sieve and mix evenly, add 5% povidone K30 in 70% ethanol solution in an appropriate amount to make a soft material, pass through a 40-mesh sieve to granulate. 50-60 ℃ oven blast drying. The dry granules are sieved through a 40-mesh sieve. Fill No. 1 capsules according to the prescription, and each capsule contains 40 mg of phytosterol.

Embodiment 3

[0182] Preparation of Phytosterol Ordinary Capsules

[0183] Prescription: Phytosterols 40mg

[0184] Povidone (K30) 160mg

[0185] Proper amount of ethanol

[0186] Magnesium Stearate 1mg

[0187] Take phytosterol, povidone and add appropriate amount of ethanol to heat and dissolve, put in a rotary evaporator to remove ethanol, cool, pulverize, pass through a 40-mesh sieve, add magnesium stearate in the prescribed amount, and mix well. Fill No. 1 capsules according to the prescription, and each capsule contains 40 mg of phytosterol.

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PUM

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Abstract

The invention discloses the application of phytosterin in preparing medicamnet for the treatment of chronic non-bacterial prostatitis and a medicament composition. The phytosterin mainly contains beta-sitosterin, stigmasterol, campesterol and or brassicasterol. The medicament composition of the invention is common tablet, capsule, granule, injection or slow-release tablet and capsule. The invention has excellent functions of anti chronic non-bacterial prostatitis, high security, and is clinically used for the treatment of chronic non-bacterial prostatitis.

Description

technical field [0001] The invention relates to plant medicine, in particular to the new medical treatment application of phytosterol, that is, the application in preparation of medicine for treating chronic non-bacterial prostatitis, and the pharmaceutical composition prepared from phytosterol. Background technique [0002] At present, the chemical components and pharmacological effects of phytosterols have been systematically studied. Phytosterol is a mixture of sterols with similar structures, mainly including β-sitosterol, stigmasterol, campesterol and brassicasterol, etc. Sitosterol and stigmasterol are the main ones (Xu Wenlin, Wang Yaqiong, etc. Solvent selection for refining phytosterols by recrystallization. Journal of Yangzhou University: Natural Science Edition, 2002, 5(1): 58-61). [0003] Phytosterols have strong pharmacological activity. Current studies have proved that phytosterols have various pharmacological effects such as lowering blood cholesterol level...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/56A61K9/00A61P13/08
Inventor 惠永正吴伟泳杨翎邓嘉元
Owner 上海药谷药业有限公司
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