Oil-in-water type emulsion composition and method for production thereof
An oil-in-water type and manufacturing method technology, applied in chemical instruments and methods, pharmaceutical formulations, transportation and packaging, etc., can solve problems such as products that are difficult to use widely, and achieve the effects of inhibiting the increase in viscosity over time and reducing costs
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Embodiment 1
[0043] Mix 22.5 parts by weight of aliphatic alcohol [SASOL company, Nacol 18-98] with 18 carbon atoms and 7.5 parts by weight of calcium carbonate [Shiraishi Industry Co., Ltd., Brilliant-1500] as water-insoluble hydrophilic inorganic fine particles , heating and melting the aliphatic alcohol with 18 carbon atoms. Then, the melt was stirred at 73° C. with a turbine blade at a peripheral speed of 5.2 m / s, while 73° C. hot water was dropped thereon. Stirring was temporarily stopped when a high-viscosity gel-like mixture was obtained, and then 69.94 parts by weight of hot water at 73° C. was added in total, and then stirring was restarted. 0.06 parts by weight of Welangam (product name) (Sanjing Co., Ltd., KIC376) was added to the resulting emulsified dispersion liquid, and cooled to obtain an oil-in-water emulsion composition. The results of the time-lapse thickening test of the sample composition of Example 1 are shown in the following "Table 1".
[0044] [Table 1]
[0045]...
Embodiment 2
[0049] Mixing 22.5 parts by weight of aliphatic alcohol [SASOL company, Nacol 18-98] with 18 carbon atoms and aluminum hydroxide as water-insoluble hydrophilic inorganic fine particles [Kanto Chemical Co., Ltd. deer special grade average particle size 0.05 μm ] 7.5 parts by weight, a sample of the oil-in-water emulsion composition was obtained by the same method as in Example 1 below. The results of the time-lapse thickening test of the sample composition of this Example 2 are shown in "Table 2" below.
[0050] [Table 2]
[0051] [Example 2: Results of time-lapse thickening test]
[0052] Measurement conditions
[0053] As shown in "Table 3" above, the viscosity of this sample was 352 mPa·s immediately after manufacture, and 370, 403, 410, and 425 mPa·s after storage at 10°C, 20°C, 30°C, and 40°C for 30 days, respectively. s. That is, there is almost no temporal change in viscosity.
Embodiment 3
[0055] Mix 22.5 parts by weight of aliphatic alcohol [SASOL company, Nacol 18-98] with 18 carbon atoms and 7.5 parts by weight of aluminum oxide [Kanto Chemical Co., Ltd. deer special grade] as water-insoluble hydrophilic inorganic fine particles, the following By the same method as in Example 1, a sample of an oil-in-water emulsion composition was obtained. The results of the time-lapse thickening test of the sample composition of Example 3 are shown in "Table 3" below.
[0056] [table 3]
[0057] [Example 3: Results of time-lapse thickening test]
[0058] Measurement conditions
[0059] As shown in "Table 3" above, the viscosity of this sample was 412 mPa·s immediately after manufacture, and 455, 461, 466, and 503 mPa·s after storage at 10°C, 20°C, 30°C, and 40°C for 30 days, respectively. s. That is, there is almost no temporal change in viscosity.
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