Compound biological medical material of biological ceramic silicon rubber

A technology of biomedical materials and bioceramics, which is applied in the field of biomedical materials and its preparation, can solve the problems of capsule contracture, poor tissue bonding of silicone rubber, single composition, etc., and achieve the effect of promoting growth and facilitating adhesion and growth

Inactive Publication Date: 2008-06-11
曾维桥
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above materials have corresponding disadvantages: hydroxyapatite ceramics and calcium phosphate ceramic particles lack structural integrity and mechanical stability, and the materials are difficult to maintain in the desired position, and the block is soft and hard, making it difficult to carve into shape
However, silicone rubber has poor tissue bonding and is easy to form a capsule, which can contract under certain conditions.
[0003] At present, commonly used biomaterials in clinical practice, such as silicone rubber, hydroxyapatite ceramics, calcium phosphate ceramics, expanded polytetrafluoroethylene, high-density polyethylene, etc., cannot have both good mechanical properties and biological properties due to their single material composition.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0015] 1) Select 30 grams of nano-hydroxyapatite ceramics and 100 grams of silicone rubber. Mix evenly in the development type rubber mixer to obtain a mixture.

[0016] 2) Preheat the metal nose prosthesis mold, and place the kneaded mixture in the metal nose prosthesis mold.

[0017] 3) Put the metal nose prosthesis mold in a vulcanizing machine for vulcanization and molding.

[0018] 4) Take out the vulcanized nasal prosthesis and vulcanize it again. The vulcanization temperature is between 150°C and 200°C.

[0019] 5) Autoclave or Co-60 sterilize the vulcanized nose valence body to make the product sterile.

example 2

[0021] a) Select 50 grams of nano-calcium phosphate ceramics and 50 grams of silicon rubber. Mix evenly in the development type rubber mixer to obtain a mixture.

[0022] b) Preheating the mold of the metal shaping plate, and placing the above kneaded mixture in the mold of the metal shaping plate.

[0023] c) placing the metal shaping plate mold in a vulcanizing machine for vulcanization and molding.

[0024] d) Take out the vulcanized shaping plate and vulcanize again, the vulcanization temperature is between 150°C and 200°C.

[0025] e) Autoclave or Co-60 sterilize the vulcanized plastic plate to make the product sterile.

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Abstract

The invention relates to biological medical material which is compounded by biological ceramics, namely, hydroxyapatite ceramics, calcium phosphate ceramics, and silicon rubber. The biological ceramics and silicon rubber compound biological medical material of the invention is used to choose corresponding dies for manufacturing artificial nose bridges, artificial mandibles, artificial temples, artificial malar bones, plastic plates, or other implanted supports. After being implanted in the body, the biological ceramics can gradually degrade peripheral tissues for gradually growing in, which can improve the growth of new bones. The surface has micro-pore type structures, which is favorable for adhesion and growth of cells. The invention provides a preparing process of the biological ceramics and silicon rubber compound biological medical material.

Description

Technical field: [0001] The invention relates to a biomedical material, in particular to a biomedical material composed of hydroxyapatite ceramics, calcium phosphate ceramics and silicon rubber and a preparation method thereof. Background technique: [0002] Due to various factors, the deformity and defect of human organs need to be reconstructed and repaired by means of tissue transplantation and tissue substitute implantation. Therefore, developing an "ideal" tissue replacement material has always been a research focus in the medical field. Hydroxyapatite ceramics, calcium phosphate ceramics and silicone rubber are commonly used clinical filling materials. The composition structure of hydroxyapatite ceramics and calcium phosphate ceramics is close to the inorganic components of human bone and tooth tissue, and has good biocompatibility and biological activity. It can be degraded and absorbed in the body, promotes the growth of new bone around it, and also has a bone-cond...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/46A61L27/10A61F2/28
Inventor 曾维桥
Owner 曾维桥
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