Composite containing pioglitazone HCL and repaglinide

Abstract

The invention relates to a composition which takes a pioglitazone hydrochloride and a repaglinide as an active ingredient and a preparation method thereof.The invention, taking the pioglitazone hydrochloride and the repaglinide as a medicinal active ingredient, is a medicinal composition mixedly formed with a carrier adoptive in pharmacy, and the invention can be prepared into oral preparations such as a troche, a capsule, a dispersible tablet, a chewable tablet, an orally disintegrating tablet, a buccal tablet, a liquid capsule, a soft capsule and a pill, etc. The composition can be used for curing type two diabetes.

Description

technical field [0001] The invention relates to a pharmaceutical composition, more specifically to an oral preparation with pioglitazone hydrochloride and repaglinide as active ingredients, and belongs to the technical field of medicine. Background technique [0002] The incidence of diabetes is still increasing year by year. China has become the hardest-hit area, and the number of diabetic patients ranks second in the world after India. According to the data provided by the World Health Organization (WHO), the prevalence of diabetes in developed countries has reached as high as 5% to 10%, and in my country it is about 3%. According to the most conservative calculation, the number of diabetic patients in China increases by one million every year. There are 2,700 new cases; by 2030, the number of diabetic patients in the world will double compared with 2000. [0003] Analysts pointed out that for some time to come, the incidence of type 1 diabetes will remain relatively stab...

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Problems solved by technology

[0012] However, after searching, there is no literature report on the compound preparation of pioglitazone hydrochloride and repaglinide