Optical power therapentic equipment

[0020] The present invention will be further described below in conjunction with the drawings and embodiments.

[0021] Please refer to figure 1 , Is a schematic diagram of the basic principle structure of the photodynamic therapy device of the present invention. The photodynamic therapy device 100 includes a treatment light source 11 and a fluorescence excitation light source 12, a light coupling module 13, an optical fiber interface 14, a fluorescence analysis module 15 and a core control module 16. The treatment light source 11 and the fluorescence excitation light source 12 are both connected to the light coupling module At 13, the optical coupling module 13 couples the obtained two lights to the same optical fiber interface 14 for output, and then a dedicated optical fiber is connected to the optical fiber interface 14 to transmit the coupled light to the target site. The optical coupling module 13 filters the fluorescence returned from the optical fiber interface 14 and transmits it to the fluorescence analysis module 15. The fluorescence analysis module 15 transmits the analytical data to the core control module 16 in real time, and the core control module 16 combines the analytical data with After the preset data is compared, a prompt signal or control instruction is issued. At the same time, the core control module 16 is connected to the treatment light source 11 and the fluorescence excitation light source 12 to control the opening and closing of the treatment light source 11 and the fluorescence excitation light source 12 respectively. When the light source 11 is turned on, it is in the treatment mode, and when the fluorescent excitation light source 12 is turned on, it is in the diagnosis mode. Therefore, the photodynamic therapy device 100 has two working modes, namely, the diagnosis mode and the treatment mode, which are respectively used for photodynamic diagnosis before and after treatment. And the light dose monitoring of the treatment process.

[0022] The working process of the photodynamic therapy device 100 is as follows: after powering on, the core control module 16 performs self-check on the working status of each peripheral module, initializes the temperature of the treatment light source 11 and the fluorescence excitation light source 12, and prompts the operation through the display screen. The operator enters basic information such as patient data, photosensitizer name, working mode, etc., and further prompts the operator to select the corresponding optical plug-in and special optical fiber, and deliver the optical fiber to the target site.

[0023] When the device is working in the diagnostic mode, the operator inputs a start command, and the core control module 16 controls the fluorescence excitation light source 12 to turn on and reads data from the fluorescence analysis module 15. The process can be continuous scanning or single point observation. The fluorescence analysis module 15 compares the analytical data with the reference data stored in the device, and then gives a positive or negative judgment result, and automatically saves the observation data for the doctor to read at any time.

[0024] When the device is working in the treatment mode, the operator inputs a start command, the core control module 16 controls the treatment light source 11 to turn on the target area, and at the same time reads data from the fluorescence analysis module 15, and combines the initial data with the device stored Comparing benchmark data, calculate the preset response volume that should be obtained in the target area. Later in the treatment process, the system will read and analyze the fluorescence data in real time, and automatically turn off the treatment light when the measured response volume reaches the preset response volume.

[0025] The core control module 16 inside the photodynamic therapy device 100 is equipped with fluorescence analysis software, which has an automatic optimization and upgrade function. That is, when the doctor enters the pathological diagnosis results and related information of each case before and after treatment into the system, the system will automatically optimize and upgrade the analysis software according to the statistical law. Therefore, as the total number of diagnosed and treated cases increases, the accuracy and coincidence rate of equipment analysis and judgment will increase.

[0026] Please refer to figure 2 ,Yes figure 1 A schematic structural diagram of an embodiment of the photodynamic therapy device 100. The photodynamic therapy device 200 includes a 630nm semiconductor laser 21, a 405nm semiconductor laser 22, an optical coupling module 23, an optical fiber interface 24, a spectrum analyzer 25, an industrial PC and an interface expansion board 26, a display and input module 27, a safety protection and alarm module 28 and power supply 29. In this embodiment, an InGaAIP semiconductor laser with a center wavelength of 630nm and a maximum output power of 2W is used as the treatment light source, and a semiconductor laser with a center wavelength of 405nm and a maximum output power of 30mW is used as the fluorescence excitation light source; the wavelength range of 450-800nm ​​is used CCD spectrum analyzer or CMOS spectrum analyzer is used as the fluorescence analysis module; an industrial PC and interface expansion board 26 are used to form the core control module. The display and input module 27 includes a display screen, a keyboard, and a mouse, and is respectively connected to the industrial control PC and the interface expansion board 26. The safety protection and alarm module 28 and the housing are connected to the industrial control PC and the interface expansion board 26. The power source 29 provides voltage to each module in the photodynamic therapy device 200.

[0027] Compared with the prior art, the photodynamic therapy devices 100 and 200 of the present invention have both diagnostic and therapeutic functions, and can realize the on-site confirmation of the light range before treatment and the individual design of the light dose, and the real-time detection and illumination of the target area response during treatment Automatic adjustment of dosage, follow-up evaluation of killing effect after treatment and early detection of tumor residue. Therefore, it is beneficial to improve the information level of the equipment, enhance the scientific nature of photodynamic therapy, and create conditions for individualized treatment.

[0028] The above detailed description is only an exemplary description, and those skilled in the art can design various implementation manners according to different actual needs without departing from the scope and spirit of the present invention.