Preparation method of magnolia bark extracts with no residual solvent, low oiliness and high content

Abstract

The invention relates to a preparation method for magnolia officinalis extract with no residue, low oiliness and high content. The invention is characterized in that tree bark, root bark and branch bark are taken as raw materials, supercritical CO2 fluid extraction and multi-stage separation technology is adopted to get magnolia officinalis extract, and the content of magnolol and honokiol is more than 90 percent. The magnolia officinalis extract has the advantages of no organic solvent residue, low oiliness, easy crushability and good dispersibility, which can be used directly in the production of dosage forms such as tablets and capsules, etc.

Description

A kind of preparation method of magnolia bark extract with no solvent residue, low oiliness and high content technical field The invention relates to a preparation method of plant active ingredient extract. Background technique Magnolia officinalis is the dry bark, root bark, or branch bark of Magnolia officinalis Rehd. et Wils. or Magnolia officinalis Rehd. et Wils. Var. biloba Rehd. et Wils. It is used as a medicine for removing dampness in Chinese medicine. The effect of eliminating phlegm, lowering Qi and eliminating fullness. Modern pharmacological studies have shown that magnolia bark has effects such as affecting gastrointestinal motility, antibacterial, antiviral, muscle relaxation, central inhibition, and antiallergic. The main active ingredients in magnolol are magnolol and honokiol. Modern studies have shown that magnolol and honokiol have strong antifungal and anti-inflammatory effects, and have good effects on the nervous system and cardiovascular and cerebr...

AI Technical Summary

Problems solved by technology

The general Magnolia officinalis extract is produced by organic solvent extraction, and the active ingredient content of the product is low, which needs to be further refined; the production efficiency is low, and the loss of solvent recovery is large; the product contains certain solvent residues, which is not conducive to the production of special products (such as medicines, daily chemical products) used in

Some people also use supercritical technology to produce, but due to the unsatisfactory separation process, the product contains more oily substances, the product is heavy in oiliness, easy to agglomerate, and poor in dispersibility, so it cannot be directly used in the production of tablets, capsules, etc. , it also needs to be treated with a certain solvent to remove oily substances