Intelligent medicine releasing capsule system for digestive canal and method

Abstract

The invention provides an enteron intelligent drug releasing capsule system and a method used for carrying out intelligent drug releasing of enteron of animal or human body. The system comprises a drug releasing electronic capsule and an information processing device; the drug releasing electronic capsule comprises a shell, a mini-typed battery, a sensor module, a drug releasing function module and a central control module; the parts are encapsulated inside the shell; the sensor module detects the physical chemistry or biochemical parameters inside the enteron with given time interval, and carries out the drug releasing intelligently according to the sensor module detection information. The system and the method of the invention can detect the physical chemistry or biochemical parameters of the enteron in real-time and control the drug releasing intelligently on the basis of the parameter processing, thus leading the drug to be released in the enteron within the best time and at the best position; the system and the method of the invention are novel noninvasine intelligent disease diagnosis and treatment system and method.

Description

Technical field: [0001] The invention relates to an alimentary canal intelligent drug-releasing capsule system and method, which are used for intelligent drug release in the intestinal tract of animals or human bodies, and belong to the technical field of biomedical engineering. Background technique: [0002] Gastrointestinal diagnosis and treatment capsule system is an important direction in the development of digestive tract diagnosis and treatment technology in recent years. With the development of microelectronics technology, some products of the electronic capsule system for gastrointestinal diagnosis and treatment with diagnosis and treatment functions have entered into clinical application. Remote drug release capsules with remote drug release function, etc. In 2001, Israel’s Given Imaging Company took the lead in launching the clinical wireless endoscope M2A, which was certified by the US FDA. The M2A capsule endoscope is 30mm long and 11mm in diameter. It uses a CM...

AI Technical Summary

Problems solved by technology

[0003] In clinical practice, some gastrointestinal diseases require local drug administration to improve curative effect and reduce side effects, such as small intestinal bleeding. May cause gut trauma

However, the current oral dosage forms mainly based on biomaterials, such as various capsule preparations, cannot accurately release the drug at the small intestinal bleeding site, and it is difficult to achieve a good therapeutic effect.

In addition, although some of the current controlled-release preparations can disintegrate according to changes in the pH of the intestinal tract, due to the great individual differences in the human body, and the disintegration of the preparation is not only affected by the pH value, it leads to Current controlled-release formulations that release drugs based on pH changes in the digestive tract are difficult to reliably control

In addition, some gastrointestinal diseases have changes in biochemical characteristics or microbial characteristics at the onset site, and the current controlled-release preparations are difficult to reliably respond to these changes and cannot release the drug at the optimal site

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