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Extracting method for kuh-seng disinfection composition and sanitizer containing the kuh-seng disinfection composition

An extraction method and disinfectant technology, which are applied in the field of disinfectants and can solve the problems of destroying effective ingredients and the like

Inactive Publication Date: 2009-04-08
CHINESE ACAD OF INSPECTION & QUARANTINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, through extraction by heat reflux method, the extract contains impurities (ineffective components) with a relative molecular mass greater than tens of thousands, and the existence of this part of impurities destroys the effect of active components.

Method used

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  • Extracting method for kuh-seng disinfection composition and sanitizer containing the kuh-seng disinfection composition
  • Extracting method for kuh-seng disinfection composition and sanitizer containing the kuh-seng disinfection composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Take 200g of crushed Sophora flavescens, put it in a drying box and dry it fully, add it to 8 times its weight in acetone and soak for 24 hours, heat and reflux the acetone solvent soaked in Sophora flavescens for 1.5 hours, and then filter out the residue of Sophora flavescens , collect the filtrate; wash the Sophora flavescens slag obtained by washing once with the above-mentioned acetone of the same weight to obtain a washing liquid, and combine the washing liquid and the above-mentioned filtrate to obtain a primary filtrate. Utilize the ultrafiltration device, adopt the polyethersulfone (PES) membrane filtration that cut-off molecular weight is 5000~10000 filtrate, obtain secondary filtrate; The solvent acetone was distilled off under the conditions to obtain the extract of Sophora flavescens, which was light brown powder after crushing. The Sophora flavescens extract contains effective bactericidal components of Sophora flavescens, and the mass content of the effec...

Embodiment 2

[0023] The Sophora flavescens extract obtained by the method of Example 1 was separated and determined by gas chromatography.

[0024] Sophora flavescens extract is dissolved in acetone, and is separated and determined by gas chromatography using XE-60 (25m, 0.25mm, 0.25μm) quartz capillary column and FID detector. The results are as follows: figure 1 and 2 shown.

Embodiment 3

[0026] The Sophora flavescens extract that obtains with embodiment 1 method prepares disinfectant.

[0027] Take 3g of Sophora flavescens extract powder, add 50ml of acetone and 50ml of emulsifier TX-10 into it, and shake well to obtain a light yellow emulsion, which is a disinfectant with a content of 3% by weight.

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PUM

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Abstract

The invention belongs to the field of disinfectants, and in particular relates to a method for extracting a sophora flavescens bactericidal component, as well as a disinfectant prepared from sophora flavescens extract containing the sophora flavescens bactericidal component. The extraction method comprises the following steps: after dried ground sophora flavescens is added to acetone and soaked, acetone solvent for soaking the sophora flavescens is heated and refluxed; sophora flavescens dregs are filtered and removed, and then a filtrate is collected; the obtained sophora flavescens dregs are washed with the acetone, so as to obtain a washing solution; the washing solution is combined with the obtained filtrate, so as to obtain a primary filtrate; the primary filtrate is filtered by use of an ultrafiltration device and a film with the interception molecular weight between 5,000 and 10,000, so as to obtain a secondary filtrate; the obtained secondary filtrate is put into a rotary evaporator to steam off the acetone solvent, so as to obtain the sophora flavescens extract; and the sophora flavescens extract contains the effective bactericidal component of the sophora flavescens. The disinfectant which is prepared by adding acetone and alkylphenol polyoxyethylene ether as an emulsifier in certain proportion to the sophora flavescens extract contains the sophora flavescens bactericidal component and has good sterilization effects.

Description

technical field [0001] The invention belongs to the field of disinfectants, and in particular relates to a method for extracting bactericidal components of Sophora flavescens, and a disinfectant prepared from extracted Sophora flavescens extract containing bactericidal components of Sophora flavescens. technical background [0002] Among the fungicides used at this stage, chemical drugs account for a considerable proportion, and the long-term use of chemical drugs has brought problems such as chemical drug residues and environmental pollution to the environment. Under the situation of increasing awareness of global environmental protection, chemical drugs are facing serious challenges, and drugs derived from natural sources are becoming a hot spot in drug research and development. Drugs derived from natural sources include drugs from plant sources, microbial sources and mineral sources, most of which are derived from plants. Most of the secondary metabolites in plants, such...

Claims

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Application Information

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IPC IPC(8): A01N65/00A01P1/00A61K36/489A61P31/04
CPCY02A50/30
Inventor 慈颖张顺合张乐王林
Owner CHINESE ACAD OF INSPECTION & QUARANTINE
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