Spray for removing peculiar smell in oral cavity

A technology of oral odor and spray, which is applied in the field of medicine, can solve the problems of poor durability and inability to maintain a fresh effect for a long time

Inactive Publication Date: 2009-04-15
靳霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most importantly, these methods of eliminating bad breath are not durable enough to provide long-term freshness

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Weigh 4g of honeysuckle, 1g of mint, 3g of clove, 6g of perilla leaf, 0.3g of borneol, 5g of sweet-scented osmanthus, 7g of green tea, 4g of licorice and 30g of water, and place them in a sealed flask. Heated in a water bath at 30° C. for 5 hours, filtered, and collected the filtrate. The filtrate, 3 g of 1% KOH aqueous solution, 3 g of sucrose, 802 g of Tween and 15 ml of water were put into a sprayer under aseptic conditions. The sprayer was purchased from Shenzhen Xinjitai Spray Pump Co., Ltd., with a volume of 50ml and a spray volume of 1ml each time.

experiment example 1

[0010] Experimental example 1: antibacterial test

[0011] Adopt classic filter paper method in this field to carry out bacteriostasis test, wherein:

[0012] 1. Materials

[0013] 1.1 Bacteria to be tested

[0014] Staphylococcus aureus (Staphylococcus aureus) ATCC 25923, Candida albicans (Candida albicans) ACTT 12228 were purchased from China Institute for the Control of Biological Products.

[0015] 1.2 Culture medium

[0016] Nutrient agar and nutrient broth were purchased from Beijing Zhongke Chenyu Experimental Equipment Co., Ltd.

[0017] 1.3 Test method

[0018] Inoculate Staphylococcus aureus and Candida albicans on the nutrient solution plane of the agar plate, and spread evenly and densely when inoculating. Take a sterile circular filter paper with tweezers, and use the spray agent in Example 1 to spray the filter paper wet, so that the droplets on the filter paper just start to drip when the filter paper stands vertically. Stick the filter paper on the cultur...

experiment example 2

[0021] Experimental example 2: Durability of eliminating bad breath

[0022] Use the spray of embodiment 1 to 10 patients who have bad breath, and everyone sprays 4 times to oral cavity. And ask another 5 people to evaluate the test results, think that the bad breath in the mouth is eliminated as 1 point, think that the bad breath in the mouth is not eliminated is 0 points, the scoring result is more than 3 points to indicate that the bad breath in the mouth is eliminated, and the scoring result is lower than 3 points. Mouth odor is not eliminated. Test results were scored every 1 hour.

[0023] The results showed that scoring was carried out immediately after use, and all 10 patients scored 5 points, indicating that the bad breath in the mouth was eliminated. It was not until 3 hours that the score was lower than 3 points for the first time. This shows that the spray of the present invention can last at least 2 hours or more. The duration of general chewing gum is within ...

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PUM

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Abstract

The invention relates to a spraying agent for eliminating oral malodor, which is produced from the following substances and pharmaceutically acceptable carriers in weight portion: 3 to 5 portions of honeysuckle, 0.5 to 1.5 portions of peppermint, 1 to 6 portions of clove, 4 to 8 portions of perilla leaf, 0.1 to 0.5 portion of borneol, 3 to 7 portions of osmanthus fragrans, 5 to 11 portions of green tea, and 3 to 5 portions of liquorice. The spraying agent for eliminating oral malodor has apparent efficacy of eliminating oral malodor, and is suitable for large-scale popularization.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a spray for eliminating bad breath in the mouth. Background technique [0002] Bad breath seriously affects people's social life, daily life, work / business interests and interpersonal relationships. In order to meet the needs of social etiquette, some people who are troubled by bad breath will seek the help of drugs, but due to the complex oral environment, there are situations of incorrect use and abuse of drugs, resulting in recurrent attacks; and drug ingredients are easy to enter the body through the mouth, Potentially harmful to the body. Most people mask bad breath with chewing gum and alcohol-based mouthwashes or breath fresheners. However, traditional chewing gum contains sugar and plasticizers, which affect health, pollute the environment and affect etiquette. Alcohol products usually taste very pungent, and alcohol is highly irritating, and long-term use will change the oral ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61K9/12A61P1/02A61K31/045
Inventor 靳霞
Owner 靳霞
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