Electrochemical tongs for developing protein molecule electronic device and method for producing the same

An electronic device and electrochemical technology, applied in the structural field of electrochemical tweezers, can solve the problems of inability to develop high-speed response capability, protein is not easily deformed, protein deformation and denaturation, etc., and achieves easy control of manufacturing conditions, simple and cheap instruments, and easy operation. Effect

Inactive Publication Date: 2009-05-06
NINGBO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The primary technical problem to be solved by the present invention is to overcome the above-mentioned existing two methods for developing protein molecular electronic devices, which cause protein deformation and denaturation due to large force, weak signal, difficult surface renewal, expensive equipment, and off-site information. 1. Insufficiency of the slow scanning speed and the inability to develop protein molecular electronic devices with high-speed response capability, provide an electrochemical clamp for developing protein molecular electronic devices, which has a slight force and the protein is not easy to deform and denature; the number of contact molecules is large, and the signal is strong; The surface is easy to update, just cut off the front end to form a new section; the instrument used is simple; the information is on-site; the electrochemical technology is diverse; the scanning speed is fast, and protein molecular electronic devices with high-speed response can be developed
[0006] Another technical problem to be solved by the present invention is to overcome the above-mentioned existing two methods of developing protein molecular electronic devices, which cause protein deformation and denaturation due to large force, weak signal, difficult surface renewal, expensive equipment, and information is not on-site. Due to the shortcomings of protein molecular electronic devices with slow scanning speed and high-speed response capability, a simple, practical, easy-to-implement, reusable, and low-cost method for making electrochemical pliers for protein molecular electronic devices is provided.

Method used

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  • Electrochemical tongs for developing protein molecule electronic device and method for producing the same
  • Electrochemical tongs for developing protein molecule electronic device and method for producing the same
  • Electrochemical tongs for developing protein molecule electronic device and method for producing the same

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Embodiment 1

[0041] In this embodiment, glass fiber is selected as the insulating base material, gold is used as the inner ring conductor 2 and the outer ring conductor 3, and ethanol and double-distilled water are used for ultrasonic cleaning, the conductive adhesive 5 and 9 are silver conductive adhesive, and the inner and outer insulating layers 4 , 12 High molecular polymers formed by polymerization. The specific production method is as follows: first place the glass fiber in acetone to reflux for 10 hours, then use ethanol and double distilled water to ultrasonically clean it, and after it is completely dried, cut off a length of 3-4 cm as the insulating substrate 1, and evaporate a layer of it on its surface Gold with a thickness of about 20nm acts as the inner ring conductor 2, and is bonded to the end of the Φ0.1mm copper wire with silver conductive glue 5 to form the inner ring conductor wire 6. The gold-plated glass fiber is immersed in phenol and 2-allyl In the phenol solution, ...

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Abstract

The invention relates to a pair of electrochemical pliers used for developing a protein molecule electronic device and a fabricating method thereof. The fabricating method is characterized in that the surface of an insulating basal material is uniformly coated with an inner layer and an outer layer of annular conductors of nanometer-level thickness, and a nanometer isolating layer of adjustable thickness is used for isolation. The annular conductors of the inner layer and the outer layer are respectively supplied with proper voltage, and electrostatic attracting force is used for clamping protein molecules causing the protein molecules to be arranged in parallel in a fixed direction; an outer circuit is used for supplying an activating signal to the protein molecules clamped by the electrochemical pliers; the relationship between an input signal and an output signal is analyzed to obtain the inner electronic transferring system of the protein molecules and develop the electronic device of the protein molecules. The electrochemical pliers provided by the invention has light action force, the shape and the quality of the protein can not easily change, touched molecule number is high, the signal is strong, the surface regeneration is easy, the used instrument is simple, the information is on-site, and the scanning speed is high. The fabricating method can be used for developing the electronic device of the protein molecules, particularly the electronic device of the protein molecules with high-speed response ability.

Description

technical field [0001] The invention relates to the technical fields of electroanalytical chemistry, molecular electronic devices, and biosensors, in particular to a structure and a manufacturing method of an electrochemical clamp that can be used for developing protein molecular electronic devices. Background technique [0002] The development trend of large-scale and ultra-large-scale integrated circuits is to continuously reduce the size of electronic devices, and has now entered the era of nanoelectronic devices. At present, there are two main ways to develop nanoelectronic devices: one is to use microelectronic processing technology to further reduce the size of traditional electronic devices, but when approaching or reaching the nanometer scale, quantum mechanical effects and thermodynamic statistical fluctuation effects gradually make the development of contemporary microelectronics are severely restricted; the second is the development of molecular electronic devices...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/30G01N33/48
Inventor 郭智勇魏丹毅王邃侯琳熙卢志强
Owner NINGBO UNIV
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