Abnormal output detection system for a biosensor

Abstract

The present invention provides a biosensor having an abnormal output detection system that determines whether an output signal from the redox reaction of an analyte has a normal or abnormal shape or configuration. The abnormal output detection system improves the accuracy and precision of the biosensor in determining whether an output signal has a shape or configuration that may not provide an accurate and / or precise analysis of a biological fluid. The biosensor generates an output signal in response to the redox reaction of the analyte. The biosensor normalizes the output signal and compares the normalized output signal with one or more control limits. The biosensor may generate an error signal when the normalized output signal is not within the control limits. The system is particularly suitable for measuring glucose using enzyme electrode of door control current analysis method, wherein the normalized signal including ration of two current values of given pulse.

Description

[0001] References to related applications [0002] This application claims priority to U.S. Provisional Application No. 60 / 746,771, entitled "Abnormal Output Detection System for a Biosensor," filed May 8, 2006, which is hereby incorporated in its entirety The contents are for reference. Background technique [0003] Biosensors typically provide analysis of biological fluids such as whole blood, urine or saliva. In general, a biosensor analyzes a sample of a biological fluid to determine the concentration of one or more analytes in the biological fluid, such as glucose, uric acid, lactate, cholesterol, or bilirubin. Such analysis can be used to diagnose and treat physiological abnormalities. For example, a diabetic patient may use a biosensor to measure glucose levels in the blood to adjust diet and / or medication. [0004] Biosensors can provide anomalous outputs during analysis of biological fluids. The abnormal output may be in response to an error during analysis of the...

AI Technical Summary

Problems solved by technology

However, these systems generally do not evaluate or determine whether the output signal from the biosensor is a normal or abnormal response from the analysis of the biological fluid

Therefore, biosensors may provide inaccurate analysis when errors are not detected by the error detection system

In addition, biosensors may provide inaccurate analysis when the error detection system does not detect errors from combinations of factors that alone would not have contributed to the error

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