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Method for extracting medicinal material from Periplaneta americana

An extraction method, the technology of Periplaneta americana, which is applied in the field of extraction technology of pharmaceutical raw materials, can solve the problems of destroying biologically active substances, etc., and achieve the effect of improving the extraction rate and reducing the generation of peculiar smell

Active Publication Date: 2009-08-12
黄少鉴
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method will destroy more biologically active substances

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Carry out the extraction of American cockroach according to the following steps:

[0021] A alcohol extraction:

[0022] 1) Kill fresh worms (Periplaneta americana), soak them in alcohol for 4 to 6 hours with 75% (concentration) alcohol in a ratio of 2:1 (alcohol: fresh worms) by weight;

[0023] 2) Put it into a low-temperature freezer and freeze it at a low temperature of minus 20°C for about 48 hours;

[0024] 3) After breaking the shell and coarse powder, place it in a multifunctional extractor, add 3 times of 70% (concentration) alcohol and soak for about 48 hours;

[0025] 4) Alcohol hot reflux extraction for 7 to 8 hours to recover alcohol, the temperature of the whole process of alcohol extraction is 65 to 75°C;

[0026] 5) Recover the medicinal liquid and put it in the separator for oil-water separation;

[0027] 6) The separated medicinal liquid is filtered through a microporous filter;

[0028] 7) Put the filtrate in a vacuum concentrator to concentrate t...

Embodiment 2

[0035] 1) Kill fresh worms (Periplaneta americana), soak them in alcohol for 4 to 6 hours with 80% (concentration) alcohol in a ratio of 3:1 (alcohol: fresh worms) by weight;

[0036] 2) Put it into a low-temperature freezer and freeze it at a low temperature of minus 20°C for about 48 hours;

[0037] 3) Put the shelled coarse powder in a multifunctional extractor, add 5 times of 70% (concentration) alcohol and soak for about 48 hours;

[0038] The following steps are the same as in Example 1.

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Abstract

The invention provides a method for extracting medicinal substances from Periplaneta American Linn, which comprises the following steps: A, alcohol extraction: killing and soaking larvae in alcohol; freezing the larvae at a low temperature; cracking shells, carrying out coarse-sizing, placing in an extractor and soaking in alcohol; thermal-reflux alcohol-extracting, recovering the drug liquid, placing in a separator and carrying out the oil-water separation; filtering and concentrating the separated drug liquid; discharging and cooling the drug liquid to obtain the medicinal substances; and B, water extraction: pouring the materials of alcohol extraction into distilled water; carrying out heating extraction; recovering and placing the drug liquid in the separator and carrying out the oil-water separation; and filtering and concentrating to obtain the medicinal substances. Compared with the prior art, the method of the invention improves the extraction yield and increases the total content of amino acid as well as the contents of polypeptide, protein, chitin, chitosan and the like in the extracted medicinal substances, and is particularly characterized in that the unpleasant odor is eliminated by low-temperature freezing before the extraction, therefore, the extracted medicinal substances have almost no unpleasant odor from the original extract while more bioactive substances are preserved.

Description

technical field [0001] The invention relates to an extraction process of medicinal raw materials, in particular to an extraction method of medicinal substances of Periplaneta americana. Background technique [0002] The American cockroach (Periplaneta American Linn) is an insect. The medicinal solution extracted from Periplaneta americana can be used in skin care products, medicines, health products, etc. It has the effect of promoting tissue growth and healing and anti-oxidation, can sober up the liver, nourish the stomach, promote the healing of gastric ulcer and duodenal ulcer, and promote inflammation It can heal ulcers and has adjuvant therapeutic effect on tumors, deficiency syndrome and tuberculosis. The method used in the existing Periplaneta americana extraction process is the traditional alcohol extraction method, most of the water-soluble amino acids have not been extracted, the extraction rate is only 8.7-10.3%, and the total amino acid content of the product is...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61P1/04A61P1/16A61P39/00
Inventor 黄少鉴廖吉陈昆昌
Owner 黄少鉴
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