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Absorbable, conglutination preventing and styptic power product and preparation method thereof

A product and absorbent technology, applied in the field of hemostatic powder and its processing, can solve the problems of poor adsorption function of hemostatic materials, inconvenient clinical use, poor safety, etc., and achieve the effect of hemostasis, convenient operation and improved safety.

Active Publication Date: 2014-03-12
张博
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] One purpose of the present invention is to solve the problem of poor adsorption function of hemostatic materials in the prior art, insufficient viscosity and inconvenient clinical use
In addition, the existing products cannot solve the problem of postoperative adhesion, and the safety of in vivo use is poor. Therefore, a soluble hemostatic powder that can stop bleeding and prevent postoperative adhesion and can be safely used in the body is provided.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] a Prepare ethanol solution with a concentration of 70%, add sodium hydroxide solution, raise the temperature to 80°C, stir evenly, add absorbent cotton fiber, perform dynamic chemical combination under stirring or ultrasonic vibration for 7 hours, then take it out.

[0013] b. Slowly add monochloroacetic acid solution to the original drug solution, put the semi-finished absorbent cotton fiber into the drug solution, continue dynamic chemical combination at 80°C for 10 hours, take it out, adjust the pH, and dry it.

[0014] c Prepare a 70% ethanol solution, add 2% disodium hydrogen phosphate, 3% sodium hydrogen phosphate, 8% Tween-80, 10% simethicone, and 16% sodium carboxymethylcellulose by weight of the semi-finished product. Raise the temperature to 35°C, stir evenly, add the semi-finished product, carry out dynamic chemical combination under the condition of stirring or ultrasonic vibration for 8.5 hours, take it out, and dry it with steam.

[0015] d Put it into a p...

Embodiment 2

[0017] a Prepare ethanol solution with a concentration of 95%, add sodium hydroxide solution, raise the temperature to 45°C, stir evenly, add absorbent cotton fiber, perform dynamic chemical combination under the condition of stirring or ultrasonic vibration for 9 hours, then take it out.

[0018] b. Slowly add monochloroacetic acid solution to the original drug solution, put the semi-finished absorbent cotton fiber into the drug solution, continue dynamic chemical combination at 75°C for 8 hours, take it out, adjust the pH, and dry it.

[0019] c Prepare an ethanol solution with a concentration of 85%, add 2.5% disodium hydrogen phosphate, 3.5% sodium hydrogen phosphate, 5% Tween-80, 7% simethicone, and 12% sodium carboxymethylcellulose by weight of the semi-finished product. Raise the temperature to 50°C, stir evenly, add the semi-finished product, carry out dynamic chemical combination under the condition of stirring or ultrasonic vibration for 6 hours, take it out, and dry ...

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PUM

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Abstract

The invention belongs to the technical field of medical materials, and in particular relates to a styptic power capable of stanching, preventing the conglutination after the operation and being used in a body and a processing method thereof. The styptic power comprises the following materials by weight percentage: 0.1 to 5 percent of disodium hydrogen phosphate, 0.1 to 8 percent of dibastic sodium phosphate, 0.1 to 10 percent of tween-80, 0.1 to 12 percent of simethicone, 0.2 to 25 percent of sodium carboxymethyl cellulose, and the balance of activated absorbent cotton fiber. The styptic power has the functions of immediately stanching, promoting the wound healing and excellently absorbing the wound, along with preventing the conglutination after the operation. The function of preventing the conglutination after the operation has important significance of relieving the pains of patients and improving the surviving quality.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to a hemostatic powder which can stop bleeding and prevent postoperative adhesion and can be safely used in the body and a processing method thereof. Background of the invention [0002] Hemorrhage is one of the main causes of death in trauma and war-injured patients, and rapid and effective control of hemorrhage can significantly reduce the death caused by hemorrhage. Powdered hemostatic products are not affected by the size and location of the wound, and have unique advantages. At present, the hemostatic powder developed at home and abroad has ARISTA TM And the products required by CN200610024198.2 are all polysaccharide microspheres, which can absorb water in blood, concentrate coagulation factors and platelets, and promote blood coagulation. The present inventors prepared velvet-like fine powder through activation treatment of absorbent cotton fibers to solve the pro...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/28A61L15/64A61L15/50
Inventor 张博
Owner 张博