Biosensor containing 3-dimensional metal nano-wire electrode which forms nano channel, manufacturing method and bio-disc system containing the biosensor

A metal nanowire, biosensor technology, applied in nanotechnology, biological testing, nanotechnology, etc., can solve the problems of low sensitivity, unsuitable for high sensitivity and effective detection, narrow measurement range, etc., to achieve convenient manufacturing, high Sensitivity and high-efficiency detection, cost-effective effect

Inactive Publication Date: 2009-11-04
KOREA INST OF SCI & TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, in this case, the probability of antigen immobilization to antibody is very low
In addition, when the antigen concentration in the sample is very low, the measurement range is narrow, resulting in low sensitivity
That is to say, traditional nanobiosensors are not suitable for highly sensitive and effective detection

Method used

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  • Biosensor containing 3-dimensional metal nano-wire electrode which forms nano channel, manufacturing method and bio-disc system containing the biosensor
  • Biosensor containing 3-dimensional metal nano-wire electrode which forms nano channel, manufacturing method and bio-disc system containing the biosensor
  • Biosensor containing 3-dimensional metal nano-wire electrode which forms nano channel, manufacturing method and bio-disc system containing the biosensor

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Embodiment Construction

[0027] Embodiments of the present invention are described below with reference to the drawings.

[0028] Figure 1B shows a schematic diagram of a three-dimensional metal nanowire electrode used in a nanobiosensor in the present invention.

[0029] Referring to FIG. 1B , according to the present invention, in a biosensor having a three-dimensional metal nanowire electrode for a nanobiosensor, metal nanowires 10 are arranged on top of other nanowires 10 with gaps formed therebetween. Accordingly, the probability of antigen immobilization on the antibody increases with the gap between the upper and lower metal nanowires 10 (hereinafter referred to as the three-dimensional metal nanowire gap) and the gap between the respective planar nanowires. Also, a large number of electrodes for electrical detection increases, thereby enhancing sensitivity.

[0030] In particular, in the case of detection using the biosensor with three-dimensional metal nanowire electrodes in the present inve...

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Abstract

A biosensor includes an upper substrate having a plurality of metallic nanowires on a lower surface thereof and an injection opening, into which a sample containing biomolecules is injected, a lower substrate having a plurality of metallic nanowires on an upper surface thereof; and a support member supporting the upper and the lower substrates, respectively, with a gap to form a nano channel. The metallic nanowires on the upper substrate and the lower substrate form 3D metallic nanowires electrodes.

Description

technical field [0001] The present invention relates to a biosensor having a three-dimensional metal nanowire electrode forming a channel, a manufacturing method thereof, and a biodisc system having the biosensor, and more particularly, relates to a method for forming a channel by forming a channel on an upper substrate and a lower substrate. A metal channel, a method for fabricating a three-dimensional metal nanowire electrode to form a channel by aligning the nanowires and combining the aligned substrates, a biosensor produced by the method, and a method for detecting biological substances by using the biosensor Molecular biodisc systems. Background technique [0002] In recent decades, people have paid more and more attention to prolonging the average human life span and predicting diseases in advance. As one of the cutting-edge fusion technologies, nanobiotechnology has emerged as a tool to prolong the average human life span and predict diseases in advance. Nano biose...

Claims

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Application Information

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IPC IPC(8): G01N33/48G03F7/00
CPCG01N33/5438G01N27/021G01N33/553B82Y15/00G01N27/3278G01N35/00B82Y35/00G01N33/48
Inventor 李炳喆文盛昱
Owner KOREA INST OF SCI & TECH
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