Treatment composition containing amlodipine series salt and pril medicament

Abstract

The invention relates to an amlodipine series salt, which particularly comprises nicotinate, camsilate, pyroglutamate, L-aspartate, maleate and mesylate. The invention also relates to a pril compoundor a pharmaceutical composition of a medicinal salt of the pril compound and a preparation method thereof, and a drug combination medicine box containing a composition of the amlodipine series salt and a composition of sartan compounds. The composition of the invention comprises the following components: a) a certain amount of an amlodipine salt; b) a certain amount of the pril compound or a medicinal salt of the pril compound; and c) a medicinal carrier or a diluting agent. The composition or the medicine box can be used for treating the patients suffering from hypertension, angina pectoris,atherosclerosis, and / or hypersphyxia and treating the patients (including the human beings) having heart danger symptoms.

Description

technical field

[0001] The present invention relates to amlodipine series salts, specifically including nicotinate, camphorsulfonate, pyroglutamate, L-aspartate, maleate and methanesulfonate, and the Composition and preparation method thereof, the present invention also relates to a medicine kit comprising the amlodipine series salt composition and the combined drug of pril. The above compositions or kits can be used to treat patients with hypertension, angina pectoris, atherosclerosis, and / or combined hypertension and patients with cardiac risk symptoms (including humans). Background technique

[0002] Hypertension has become one of the main killers endangering human health. At present, the incidence of hypertension in some European and American countries has reached 20%. According to statistics, 43 million people in the United States suffer from hypertension; the average incidence of hypertension in my country is 11.88%, and more than 140 million people in my country suff...

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