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Traditional Chinese medicine volatile oil composition for treating gastrointestinal dysfunction or irritable bowel syndrome (IBS), and preparation method and applications thereof in preparation of medicaments

A technology for irritable bowel syndrome and gastrointestinal dysfunction, which is applied in the field of composition of effective parts of traditional Chinese medicine, can solve problems such as incomplete clarity of effective substances, restrictions on the application effect of medicinal materials, and unstable clinical curative effect, so as to achieve enhanced clinical curative effect and improved drug efficacy. The quality is stable and controllable, and the formulation of drug quality standards and quality control have targeted effects

Inactive Publication Date: 2012-03-21
阳信县润田棉业有限公司
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  • Summary
  • Abstract
  • Description
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AI Technical Summary

Problems solved by technology

However, due to the fact that its active substances are not completely clear, there are problems such as complex preparation process, difficult quality control, unstable clinical curative effect, and inconvenience for patients in practical application.
These problems have seriously restricted the application effect of these medicinal materials

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] The tangerine peel raw material is crushed into coarse powder, and the volatile oil is extracted by steam distillation. Put the coarse powder of the medicinal material in a round-bottomed flask, soak in 6 times the amount of water for 3 hours, extract the volatile oil by steam distillation for 8 hours, collect the volatile oil separately, add anhydrous sodium sulfate to dry, and filter to obtain 3.5 g of volatile oil of tangerine peel. Wherein the content of D-limonene is 60.0%.

Embodiment 2

[0077] Embodiment 2 is substantially the same as embodiment 1, but collects and obtains 4.4 grams of volatile oil. Wherein the content of D-limonene is 70.5%. All the other are with embodiment 1.

Embodiment 3

[0078] Embodiment 3 is substantially the same as Embodiment 1, but collects and obtains 2.4 grams of volatile oil. Wherein the content of D-limonene is 80.0%. All the other are with embodiment 1.

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Abstract

The invention relates to a traditional Chinese medicine volatile oil composition for treating gastrointestinal dysfunction or irritable bowel syndrome (IBS), and a preparation method and applications thereof in the preparation of medicaments. The traditional Chinese medicine volatile oil composition is characterized by comprising the following components in parts by weight: 0-3 parts of patchoulivolatile oil, 0-4 parts of atractylodes macrocephala volatile oil and 0-8 parts of orange peel volatile oil, wherein the parts of at least two components by weight are greater than 0. In the preferable scheme, the content of patchoulenone or patchouli alcohol accounts for 4-55% of the total content of the traditional Chinese medicine volatile oil composition; the content of atractylone accounts for 8-65% of the total content of the traditional Chinese medicine volatile oil composition, and the content of D-limonene accounts for 15-75% of the total content of the traditional Chinese medicine volatile oil composition. Compared with the compound crude extract, the traditional Chinese medicine volatile oil composition of the invention has a qualitative leap. The traditional Chinese medicine volatile oil composition can gather effective components, enhance the pharmacological action and the clinical curative effect, reduce the clinical dosage and be beneficial to enhancing quality control level.

Description

technical field [0001] The present invention relates to a composition of effective parts of traditional Chinese medicine, in particular to a composition of Chinese medicine volatile oil for treating gastrointestinal dysfunction, a preparation method of the composition of Chinese medicine volatile oil, and the use of the composition of Chinese medicine volatile oil in preparing a medicine for treating gastrointestinal dysfunction in the application. The traditional Chinese medicine effective part composition can be used for treating gastrointestinal dysfunction, especially for treating irritable bowel syndrome. Background technique [0002] Gastrointestinal dysfunction is a common clinical functional intestinal disease, accounting for about 40-60% of gastrointestinal diseases. Among them, the prevalence of irritable bowel syndrome (IBS) in adults is 10% to 22%, and it is slightly more common in women. Its main clinical manifestations are abdominal pain, diarrhea, constipati...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/53A61K36/752A61P1/00
Inventor 杨星昊郭升吴剑波谷春先倪婷婷
Owner 阳信县润田棉业有限公司
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