Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Positioning device for active/passive exercise training device for simulated weightless tail-suspended rat

A positioning device and rat technology, which is applied in the field of aerospace biomedical engineering research, can solve the problems of quantitative monitoring of active and passive training of rats, and the inability to maintain the angle of rat tail suspension, etc., and achieve the effect of consistent trajectory

Inactive Publication Date: 2010-05-12
BEIHANG UNIV
View PDF1 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In order to overcome the problems that the rat tail hanging angle cannot be maintained in the current rat tail hanging training device, and the active and passive training of rats cannot be quantitatively monitored and controlled, the present invention provides a simulated weightlessness state that can maintain the same tail hanging angle Next, a training device for active / passive controllable and quantitative exercise training of rats, which is used to study and find and optimize effective exercise methods against weightlessness bone loss

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Positioning device for active/passive exercise training device for simulated weightless tail-suspended rat
  • Positioning device for active/passive exercise training device for simulated weightless tail-suspended rat
  • Positioning device for active/passive exercise training device for simulated weightless tail-suspended rat

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment 1 Keeping the same training angle under weightless conditions

[0047]During use, earlier the rat fixed box 104 is taken off, the tail of the rat is mentioned, the opening of the rat fixed box 104 is approached to the rat head, and the habit of drilling holes of the rat is utilized to allow the rat to drill into the rat fixed box 104, Afterwards, the rat fixing box 104 is connected with the fixing base 103 using the hook 303 . Adjust the length of the rat position adjustment bolt 302 in the rat fixing box 104 , and adjust the position of the fixing seat 103 on the base 101 , so that the rat's hind limbs can pass through the rat's hind limbs through the hole 205 . Then the tail of the rat is suspended on the tail ring 108, and the rat foot is fixed on the left / right hindlimb resistance exercise device 105 / 106 of the rat with medical adhesive tape (the two are symmetrical structures, and one side can be selected as required) Or both sides carry out training si...

Embodiment 2

[0048] Embodiment 2 Only the hind limbs are trained

[0049] No matter it is the control group or the active / passive training group, the whole limbs of the rats are fixed in the rat fixing box 104 except the hind limbs, and its movement is restricted, and the active / passive exercise training is only carried out for the hind limbs, effectively excluding The interference of other limb movements of rats to the experiment.

Embodiment 3

[0050] Example 3 Angle adjustable active training

[0051] If the backguy 409 is not connected to the joint 410, and the rat fixing box adopts an integrated design, the device such as Figure 5 Shown. Active exercise training can only be performed on the hind limbs of the rats, and the angle of the tail suspension of the rats can be adjusted. When the soles of the rats are stimulated by the arc pulses of high voltage and low current released by the electrodes connected to the pedal 401, the large The mouse will actively contract the hind limbs to avoid the pain caused by the click, thereby lifting one end of the movement trajectory limiting plate 407. In the process, it is necessary to overcome the resistance of the load rubber band 403, and the lifting height is determined by the rat movement limiting rod 408, thereby Complete the training of rats actively contracting hind limbs against a certain resistance (or no resistance) to carry out active resistance movement. The movem...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a tail-suspended rat positioning device, which comprises a tail suspending device, a rat fixing box, a trunk positioning device and an angle control device, wherein the rat fixing box is used for accommodating the head and the trunk part of a rat; the trunk positioning device is used for fixing the trunk of the rat; and the angle control device is used for controlling an angle between the rat fixing box and a base of the tail-suspended rat positioning device. The invention also provides an active / passive exercise training device for the tail-suspended rat, which comprises a rat hind limb exercise device, a track control device, an active exercise training device and a passive exercise training device, wherein the rat hind limb exercise device is used for performing active or passive exercise training on the hind limbs of the rat; the track control device is used for limiting the motion range of the hind limbs of the rat; the active exercise training device is used for performing active exercise training on the hind limbs of the rat; and the passive exercise training device is used for performing passive exercise training on the hind limbs of the rat. The devices can keep the tail suspending angle of the rat unchangeable, namely keep a simulated weightless state during exercise training, and can control the active / passive training for the rat to perform quantitative training.

Description

[0001] This application is a divisional application of Chinese Patent Application No. 200810114305.X. technical field [0002] The invention relates to the research field of aerospace biomedical engineering, and more specifically relates to a positioning device capable of performing active / passive exercise training on tail-suspended rats under simulated weightlessness conditions. Background technique [0003] Astronauts will suffer severe weightlessness bone loss when they enter space. The average weight-bearing bone loss is 1.0-1.6% per month, and the maximum can reach 13.6%. The loss rate is much higher than the annual bone loss rate of women after menopause (3%). It will directly affect the health and work ability of astronauts. Data from animal experiments suggest that exercise training is a safe and effective measure against weightlessness-induced bone loss. Due to the limitation of space experiments, the current research data in this area are mainly obtained through t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A01K15/02
Inventor 孙联文谢添樊瑜波贡向辉
Owner BEIHANG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com