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Process for producing ginkgo extract

A technology of ginkgo extract and production process, which is applied in the field of production technology of ginkgo extract, can solve the problems of low content of active ingredients, difficulty in obtaining high-quality ginkgo biloba extract, low quality of ginkgo leaves, etc. Effect

Inactive Publication Date: 2010-05-19
应维强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, the extraction methods used for Ginkgo biloba mainly contain the following: 1. Water extraction-resin method; 2. Ethanol extraction method; 3. Acetone extraction method, etc. There is a shortcoming in both, that is, the content of active ingredients extracted is low. Moreover, due to the influence of climate and collection time, the quality of ginkgo leaves is not high at present, and the active ingredient content of ginkgo leaves used for extraction is getting lower and lower. , in this case, it is often difficult to obtain high-quality Ginkgo biloba extract using traditional production techniques

Method used

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  • Process for producing ginkgo extract
  • Process for producing ginkgo extract
  • Process for producing ginkgo extract

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Embodiment Construction

[0021] combine figure 1 Shown, the production technology of ginkgo extract of the present invention may further comprise the steps:

[0022] 1. Extract the active ingredients of Ginkgo biloba

[0023] 1.1. Lixiviation: add 8 times 50-70% ethanol to the collected ginkgo leaves and extract the ginkgo leaves for 3 times, the first time is 3 hours, the second time is 2.5 hours, the third time is 2 hours, The extraction temperature is 70 degrees, and then the extract is collected.

[0024] 1.2. Ethanol recovery: Evaporate the extract in vacuum, recover ethanol, add water to the extract and cool it for later use.

[0025] 1.3. Centrifugation: The extract was subjected to three-stage centrifugation at 1000 rpm, 4400 rpm, and 14000 rpm, respectively, and the supernatant was collected after centrifugation. Among them, the first stage of centrifugation is mainly to remove large particles of impurities in the extract, the second stage of centrifugation is mainly to remove small partic...

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Abstract

The invention relates to a process for producing ginkgo extract and belongs to the technical field of plan extraction. The process comprises the following steps of: adding ginkgo leaves serving as raw materials into 50 to 70 percent ethanol of which the weight is eight times that of ginkgo leaves serving as the raw materials to perform leaching three times, wherein the leaching temperature is 70 DEG C; collecting extracting solution, evaporating the extracting solution under vacuum, recovering ethanol, centrifuging the extracting solution and collecting supernatant solution; and subjecting the extracting solution to the centrifugal treatment by a macroporous resin chromatographic column of which the diameter-to-height ratio is 1:10, leaching the extracting solution in turn with 5 to 15 percent ethanol until the eluate is clear and bright, desorbing the extracting solution with 75 percent ethanol, after desorption, collecting desorbing solution, allowing the desorbing solution to pass through a macroporous resin chromatographic column of which the diameter-to-height ratio is 1:30, collecting the desorbing solution, decompression-recovering ethanol, condensing the desorbing solution into thick paste, and vacuum-drying the thick paste to obtain the ginkgo extract. The process adopts multiple leaching and multistage centrifuging, and also adopts a double-time desorbing method of coarse extraction and refined extraction, so that the contents of the active components are greatly improved; and the ginkgo extract with different ratios of active components can be prepared as required.

Description

technical field [0001] The invention relates to a production process of ginkgo extract, which belongs to the technical field of plant extraction. Background technique [0002] At present, Ginkgo extract is more and more favored by people because of its ability to improve cardiovascular and cerebrovascular circulation, treat cardiovascular and cerebrovascular diseases, improve memory, and delay aging. At present, the active ingredients extracted from Ginkgo are mainly Ginkgo flavonoids and Esters, the level and relative proportion of its content determine the quality and price of the product. At present, the extraction methods used for Ginkgo biloba mainly contain the following: 1. Water extraction-resin method; 2. Ethanol extraction method; 3. Acetone extraction method, etc. There is a shortcoming in both, that is, the content of active ingredients extracted is low. Moreover, due to the influence of climate and collection time, the quality of ginkgo leaves is not high at pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/16A61P9/00A61K127/00
Inventor 应维强应维潮应浩应诗雨
Owner 应维强
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