Method for preparing Chinese medicinal stomach medicament preparation and quality test method thereof

A quality inspection method and technology for gastric medicine, which are applied in the directions of pharmaceutical formulations, pill delivery, measuring devices, etc., can solve the problems of inability to determine the source of tetrahydropalmatine, low accuracy and reliability, complicated preparation methods, etc. The effect of production cycle, easy production operation and simple preparation method

Active Publication Date: 2010-05-19
XIAN BEILIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

[0002] The gastric medicine capsules currently included in the sixth volume of "Drug Standards of the Ministry of Health of the People's Republic of China Chinese Medicine Prescription Preparations" have a cumbersome preparation method and need to be prepared into granules of four different colors. The granulation process is complicated and inconvenient to operate. There are 5 identification items in the detection method of gastric medicine capsules contained in the minis...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Corydalis (vinegar) 120g, sea octopus (bleached) 60g, Tumuxiang 60g, alum (calcined) 90g, egg shell (fried) 120g, calcined mother-of-pearl 120g, Corydalis plus 1% glacial acetic acid solution, decocted 3 times, Combine the decoctions, filter, let stand, take the supernatant, condense into a thick paste; the other five flavors such as inulin are crushed into fine powder, mixed well, mixed with the above thick paste, combined to make concentrated pills.

[0020] The quality testing method of gastric pills is as follows:

[0021] Identification:

[0022] (1) Take this product, pulverize it, take the powder and observe it under a microscope: a small number of reticulate ducts are complete, and fragments are visible, with different sizes. The wood fiber is long fusiform or broken into long strips, with oblique holes.

[0023] (2) Take 4g of this product, grind it finely, add 30ml of petroleum ether (30℃~60℃), soak in cold overnight, filter, evaporate the filtrate to drynes...

Embodiment 2

[0030] Corydalis (vinegar) 120g, sea octopus (bleached) 60g, Tumuxiang 60g, alum (calcined) 90g, egg shell (fried) 120g, calcined mother-of-pearl 120g, Corydalis plus 1% glacial acetic acid solution, decocted 3 times, Combine the decoctions, filter, let stand, take the supernatant, condense into a thick paste; crush the other five flavors such as Tumuxiang into fine powder, mix well, mix well with the above thick paste, add appropriate amount of starch to granulate, mix well, and make into capsules.

[0031] The quality testing method of Stomach Medicine Capsules is as follows:

[0032] Identification:

[0033] (1) Take this product and observe under a microscope: a few of the reticulated catheters are intact, and the fragments are visible and vary in size. The wood fiber is long fusiform or broken into long strips, with oblique holes.

[0034] (2) Take 4g of this product, grind it finely, add 30ml of petroleum ether (30℃~60℃), soak in cold overnight, filter, evaporate the ...

Embodiment 3

[0041] Corydalis (vinegar) 120g, sea octopus (bleach) 60g, Tumuxiang 60g, alum (calcined) 90g, egg shell (fried) 120g, calcined mother-of-pearl 120g, Corydalis plus 1% glacial acetic acid solution, decoct 3 times, Combine the decoctions, filter, let stand, take the supernatant, concentrate into a thick paste; the rest of the five flavors such as inulin are crushed into fine powder, mix well, mix well with the above thick paste, add appropriate amount of powdered sugar and dextrin, and granulate , mix well, and make granules.

[0042] The quality testing method of Weiyao granules is as follows:

[0043] Identification:

[0044] (1) Take this product and observe under a microscope: a few of the reticulated catheters are intact, and the fragments are visible and vary in size. The wood fiber is long fusiform or broken into long strips, with oblique holes.

[0045] (2) Take 4g of this product, grind it finely, add 30ml of petroleum ether (30℃~60℃), soak in cold overnight, filter...

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Abstract

The invention belongs to the technical field of Chinese medicaments, in particular relates to a method for preparing a Chinese medicinal stomach medicament preparation and a quality test method thereof. The conventional preparation method is fussy, needs to prepare particles in four different colours, and has complicated granulation process and inconvenient operation; and the conventional test method does not have very high accuracy and reliability, and cannot determine the source of contained tetrahydropalmatine. The method for preparing the Chinese medicinal stomach medicament and the quality test method thereof, the Chinese medicinal stomach medicament consists of rhizoma corydalis (vinegar processed), drift cuttlebone, elecampane, calcined alum, fried chicken eggshell and calcined nacre. The Chinese medicament treats ache, stops pain, and is used for treating gastric cavity ache, acid stomach, and noisy acid regurgitation caused by liver-stomach disharmony. The method for preparing the Chinese medicinal stomach medicament preparation of the invention is simple and easy to operate, simplifies preparation processes, and ensures the uniformity of a product better; and the quality test method has simple operation, and accurate and reliable testing result.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a preparation method and a quality detection method of a traditional Chinese medicine stomach medicine preparation. Background technique [0002] The gastric medicine capsules currently included in the sixth volume of "Drug Standards of the Ministry of Health of the People's Republic of China Chinese Medicine Prescription Preparations" have a cumbersome preparation method and need to be prepared into granules of four different colors. The granulation process is complicated and inconvenient to operate. There are 5 identification items in the detection method of gastric medicine capsules contained in the ministerial standards, three of which are identified by chemical methods, and the other two are microscopic identification and thin-layer chromatography identification. TLC identification is mainly through the use of tetrahydropalmatine A control is...

Claims

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Application Information

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IPC IPC(8): A61K36/66A61K9/16A61K9/20A61K9/48A61P1/04G01N30/90G01N30/36A61K35/56A61K35/54A61K33/06A61K35/57A61K35/618
Inventor 黄小华付彬张浩石丽
Owner XIAN BEILIN PHARMA
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