Method for preparing brain-nourishing capsule oral solid preparation

A technology of solid preparations and Yinao capsules, which is applied in the field of medicine, can solve the problems of low bioavailability of Yinao capsules after oral administration, and achieve good disintegration time limit, quick effect, and short course of treatment

Inactive Publication Date: 2010-06-23
WUHU LUYE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The invention provides a preparation method of an oral solid preparation of Yinao Capsules, which solves the problem of low bioavailability of Yinao Capsule...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A preparation method of Yinao capsule oral solid preparation, characterized in that: comprising the following steps:

[0020] (1), each raw material component is taken by weight ratio: Yaojiajiao 386, polygala 1933, keel 3873, ganoderma lucidum 3873, schisandra 493, Radix Ophiopogon japonicus 1933, Shichangpu 1933, Codonopsis 1110, ginseng 666, Poria cocos 3873 for later use;

[0021] (2), pulverization: first pulverize the ginseng after weighing and the 1 / 4 Poria cocos that take by weighing into coarse powder, then through superfine pulverization, make it become the superfine powder of particle diameter≤10 μm;

[0022] (3), heat and melt the weighed tortoise shell glue, and set aside; add water to decoct the remaining three-quarters of Poria cocos and other raw material components twice, for the first time for 3 hours, for the second time for 2 hours, after decocting Filtrate, combine the filtrate, add the tortoise shell glue that dissolves, concentrate into a thick ex...

Embodiment 2

[0025] (1), each raw material component is taken by weight ratio: Yaojiajiao 386, polygala 1933, keel 3873, ganoderma lucidum 3873, schisandra 493, Radix Ophiopogon japonicus 1933, Shichangpu 1933, Codonopsis 1110, ginseng 666, Poria cocos 3873 for later use;

[0026] (2), pulverization: first pulverize the ginseng after weighing and the 1 / 4 Poria cocos that take by weighing into coarse powder, then through superfine pulverization, make it become the superfine powder of particle diameter≤10 μm;

[0027] (3), heat and melt the weighed tortoise shell glue, and set aside; add water to decoct the remaining three-quarters of Poria cocos and other raw material components twice, for the first time for 3 hours, for the second time for 2 hours, after decocting Filtrate, combine the filtrate, add the tortoise shell glue that dissolves, concentrate into a thick extract;

[0028] (4) Spray-dry the extract into extract powder, add superfine powder of ginseng and poria cocos, diluent lactos...

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Abstract

The invention discloses a method for preparing brain-nourishing capsule oral solid preparation. Ginseng and partial Pachyma cocos in raw materials are superfine crushed for use; the rest Pachyma cocos and other seven medicinal materials such as polygala root and the like are extracted, concentrated and combined with dissolved tortoise-shell glue into extract, and superfine ginseng and Pachyma cocos powder, a proper amount of diluting agent and disintegrating agent are added, spray-dried and made into extract powder; or the extract is spray-dried and made into extract powder, and superfine ginseng and Pachyma cocos powder, a proper amount of diluting agent and disintegrating agent are added and evenly mixed; and filling is conducted to obtain. The invention makes a major improvement to the brain-nourishing capsule by applying the modern pharmaceutical technology and improves the bioavailability of the brain-nourishing capsule oral medicine, so the therapeutic effect of the brain-nourishing capsule oral medicine is fully exerted and the patient can use the medicine conveniently.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a preparation method of Yinao capsule oral solid preparation. Background technique [0002] Yinao capsule is an oral solid preparation of traditional Chinese medicine with the functions of nourishing qi and nourishing yin, nourishing kidney and brain, improving intelligence and calming the nerves. Kidney insufficiency, patients with both qi and yin deficiency. The Yinao Capsules sold on the market only use simple crushing technology for ginseng and poria cocos, and the drug particles are large, which is not conducive to human absorption and low bioavailability. Contents of the invention [0003] The invention provides a preparation method of an oral solid preparation of Yinao Capsules, which solves the problem of low bioavailability of Yinao Capsules in oral administration, improves the bioavailability of Yinao Capsules in oral administration, and fully exerts its therapeutic effect ,...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61K9/48A61K47/34A61K47/38A61P25/20A61P25/28A61K35/56A61K35/02A61K35/586A61K47/10
Inventor 杨荣兵赵剑梁亮
Owner WUHU LUYE PHARMA
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