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Drug for treating cardiovascular and cerebrovascular diseases and preparation method thereof

A technology for cardiovascular and cerebrovascular diseases and drugs, applied in the field of drugs for the treatment of cardiovascular and cerebrovascular diseases and its preparation, can solve the problems of expensive treatment, unacceptable by families, and rising average mortality of patients, and achieve no toxic side effects and prevent malignant The effect of unimpeded disease and twelve meridians

Active Publication Date: 2013-06-12
BEIJING INCREASEPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Experts said: Although stents and bridges have temporarily passed the dangerous period for some critically ill patients, the average mortality rate of patients within five years has increased by 13% to 21.3% respectively, and the treatment is expensive, which is difficult for ordinary families to accept

Method used

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  • Drug for treating cardiovascular and cerebrovascular diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The preparation of pharmaceutical composition of the present invention:

[0039] a) Take by weighing 12kg of Salvia miltiorrhiza, 6kg of Panax notoginseng, 10kg of ginkgo biloba, 9kg of angelica, and 20kg of astragalus for subsequent use;

[0040] b) adding 8 times the amount of 60% ethanol to Danshen, Panax notoginseng, Ginkgo biloba, Angelica and Astragalus, and extracting twice;

[0041] c) merging the filtrates, reclaiming ethanol to obtain a dilute extract;

[0042] d) add water to dissolve the dilute extract, and filter;

[0043] e) Concentrate the filtrate to an extract with a relative density of 1.35-1.39 (55°C), and set aside;

[0044] f) Weigh polyethylene glycol 4000 and polyethylene glycol 6000 in a ratio of 3:1 and mix a total of 50kg, heat to a temperature of 90-100°C to melt them all;

[0045] g) Add the spare extract and make the material for 20-120 minutes;

[0046] h) move to the drip irrigation of the dripping pill machine where the tank temperature...

Embodiment 2

[0050] The preparation of pharmaceutical composition of the present invention:

[0051] a) Take by weighing 12kg of Salvia miltiorrhiza, 6kg of Panax notoginseng, 10kg of ginkgo biloba, 9kg of angelica, and 20kg of astragalus for subsequent use;

[0052] b) adding 8 times the amount of 60% ethanol to Danshen, Panax notoginseng, Ginkgo biloba, Angelica and Astragalus, and extracting twice;

[0053] c) merging the filtrates, reclaiming ethanol to obtain a dilute extract;

[0054] d) add water to dissolve the dilute extract, and filter;

[0055] e) Concentrate the filtrate to an extract with a relative density of 1.35-1.39 (55°C), and set aside;

[0056] f) Weigh polyethylene glycol 4000 50kg and heat it to a temperature of 90-100°C to melt it completely;

[0057] g) Add the spare extract and make the material for 20-120 minutes;

[0058] h) move to the drip irrigation of the dripping pill machine where the tank temperature is maintained at 90°C;

[0059] i) Drop the drug so...

Embodiment 3

[0062] The preparation of pharmaceutical composition of the present invention:

[0063] a) Take by weighing 12kg of Salvia miltiorrhiza, 6kg of Panax notoginseng, 10kg of ginkgo biloba, 9kg of angelica, and 20kg of astragalus for subsequent use;

[0064] b) adding 8 times the amount of 60% ethanol to Danshen, Panax notoginseng, Ginkgo biloba, Angelica and Astragalus, and extracting twice;

[0065] c) merging the filtrates, reclaiming ethanol to obtain a dilute extract;

[0066] d) add water to dissolve the dilute extract, and filter;

[0067] e) Concentrate the filtrate to an extract with a relative density of 1.35-1.39 (55°C), and set aside;

[0068] f) Weigh polyethylene glycol 6000 50kg, heat it to a temperature of 90-100°C, and make it completely melt;

[0069] g) Add the spare extract and make the material for 20-120 minutes;

[0070] h) move to the drip irrigation of the dripping pill machine where the tank temperature is maintained at 90°C;

[0071] i) Drop the dru...

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Abstract

The invention discloses a drug for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. The drug is prepared by danshen root, sanchi, ginkgo leaf, angelica and Astragali radix according to certain weight ratio. The drug of the invention has the efficacy of treating the cardiovascular and cerebrovascular diseases.

Description

technical field [0001] The invention relates to a medicine for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. belongs to the field of pharmaceuticals. Background technique [0002] Cardiovascular and cerebrovascular diseases are collectively referred to as cardiovascular diseases and cerebrovascular diseases. Generic name for disease. Diseases that occur in the arteries of the heart are called cardiovascular diseases, mainly including: myocardial infarction, coronary heart disease, myocardial infarction, etc. The lesions that occur in the cerebral arteries are called cerebrovascular diseases, mainly including cerebral hemorrhage, cerebral thrombosis, and cerebral embolism. [0003] In the past 30 to 40 years, due to the improvement of people's living standards and sanitary conditions, the incidence of various infectious diseases has been greatly reduced. However, chronic diseases have become the most important diseases that endanger...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/537A61P9/10A61P3/06
Inventor 高丽
Owner BEIJING INCREASEPHARM CORP LTD
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