Preparation method of garden burnet solid preparation with low dose

Abstract

The invention discloses a preparation method of a garden burnet solid preparation with low dose. The preparation method comprises the following steps of: (1) taking 1 to 10 parts by weight of garden burnet and pulverizing into fine powder; (2) taking 90 to 99 parts by weight of auxiliary materials, wherein the auxiliary materials comprise sucrose and starch; (3) taking part of the sucrose and the starch in the step (2) and preparing an adhesive; (4) mixing the fine powder obtained in the step (1) and the residual auxiliary materials in the step (2) to obtain an mixture; (5) adding the prepared adhesive into the mixture obtained in the step (4), granulating, drying, pulverizing and then mixing; and (6) granulating by using the residual part of the adhesive and / or water or the ethanol solution with the volume concentration of 5 to 40 percent, drying, sieving and then preparing a tablet, a capsule, a pill or granules. The garden burnet preparation obtained by the method has uniform content of the garden burnet, quick disintegration, good curative effect and safe, effective and controllable clinical use.

Description

A kind of preparation method of low-dose burnet solid preparation technical field The invention relates to a preparation method of low-dose burnet solid preparation, belonging to the field of pharmaceutical preparations. Background technique Burnet is a perennial herb of the family Rosaceae. As a commonly used traditional Chinese medicine, Burnet has the functions of cooling blood to stop bleeding, clearing heat, detoxifying, reducing swelling and astringing sores. Modern research shows that Burnet has various pharmacological activities such as hemostasis, anti-inflammation, promoting wound healing, antibacterial, etc., and has the effect of treating leukopenia. effect. The drug standard No. WS-11020 (ZD-1020)-2002 of the Drug and Food Administration of the People's Republic of China discloses the prescription of Sanyu Shengbai Tablets: Burnet 5g, sucrose 32g, dextrin 47g, starch 16g, made into 1000 Sanyu Shengbai Tablets; the preparation method of Sanyu Shengbai Tablet...

AI Technical Summary

Problems solved by technology

In summary, the method for preparing low-dose Burnet preparations disclosed in the prior art cannot achieve the technical effect that the active ingredient of the low-dose Burnet preparation——the Burnet is evenly distributed in the preparation

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