Compound lidocaine emulsifiable paste and preparation method thereof

A technology for lidocaine and cream, applied in ointment delivery, pharmaceutical formula, emulsion delivery, etc., can solve the problems of long production cycle, unstable product quality, high energy consumption, etc., to enhance safety and save equipment investment Effect
CN101816642BActive Publication Date: 2011-06-29北京中泰邦医药科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
北京中泰邦医药科技有限公司
Publication Date
2011-06-29

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Abstract

The invention discloses a compound lidocaine emulsifiable paste and a preparation method thereof. Each 10kg of the compound lidocaine emulsifiable paste comprises the following components according to the weight: 50-1000g of base lidocaine, 50-1000g of base prilocainum, 10-500g of polyoxyethylene hydrogenated castor oil, 10-300g of Carbomer, 40-200g of sodium hydroxide and the balance of pure water. The invention increases clinical use security through releasing lidocaine and prilocainum in base modes to the subcutaneous layer with the depth of 5mm without containing a penetrating agent or a surface active agent component, which is particularly suitable for children patients and patients for face beauty. Through improvement on production process steps, the invention enables the productionoperation to become easy and feasible, is easy to control the product quality and increases the product stability. The whole production cycle is only half day, and the production efficiency is improved by more than 3 times, thereby the raw materials are saved and the production cost is reduced.
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Description

Technical field

[0001] The invention involves a medical cream and its preparation methods. Background technique

[0002] Traditional compound riberine cream needs to be added with osmotic agents, such as: nitrogen ketones and surfactants such as: Twen 80.The purpose is to destroy the skin epidermis tissue to increase the infiltration effect of the subcutaneous.However, this is damaged to the skin and cannot achieve the purpose of safe medication.Twen 80 has a strong function of rupture cell membranes and causes irritation. The medical community confirms that Twen 80 can cause allergic reactions, including allergic symptoms such as shock, dyspnea, hypertension, vascular edema, and rubella.These adverse reactions can be very serious in clinical experiments and reports.Therefore, the use of Twen 80 has strict restrictions. It is an auxiliary material with potential unsafe. Improper use will have a great impact on human health.The viral reaction generated by this will exceed the bene...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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