Remedy for relieving skin troubles comprising morphinan derivative or pharmacologically acceptable acid addition salt thereof as the active ingredient

Abstract

It is intended to provide a therapeutically useful novel drug which exerts a skin moisturizing effect on the skin suffering from functional disorders caused by various factors so as to relieve skin troubles such as dry skin, chapped skin, dullness accompanying horny layer thickening and so on. Namely, a remedy for relieving skin troubles which contains, as the active ingredient, a compound having a specific morphinan skeleton that is typified by a compound (1) represented by the following structural formula (II) or a pharmacologically acceptable acid addition salt thereof.

Description

technical field The present invention relates to a novel medicament for providing a morphinan derivative or a pharmacologically acceptable acid addition salt thereof, which is useful for the treatment of improving skin properties through the moisturizing effect of the skin. Background technique Rough skin, dryness, and dullness of the skin are known to be caused by a decrease in the skin barrier function. To improve skin properties, lotion, foundation, lotion, horse oil, ointment, etc. have been used conventionally. Examples of medicines for improving skin properties include heparin analogues such as Hirudoid, airleet, Kuradoid, Seleloiz, and Besoften, or urea, hyaluronic acid, and collagen for external use. etc., they exist in prescriptions for sebum deficiency, progressive palmar keratoderma, etc. as indications. In addition, cosmetics containing extracts obtained by extracting the roots, rhizomes, or leaves of bitter bamboo, light bamboo, and monsophyllum with a hydrophi...

AI Technical Summary

Problems solved by technology

Therefore, there is no disclosure about the skin condition improving effect of the active ingredient having a specific morphinan skeleton in the present invention

Images