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Technology for extracting Chinese angelica and lightyellow sophora root

An extraction process and technology of Angelica sinensis, which is applied in the field of the extraction process of Angelica Sophorae Radix, can solve the problems of inconvenience in taking, many impurities, easy to mildew, etc.

Active Publication Date: 2012-10-10
王英姿
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] The present invention aims at the current Angelica Kushen Pills, which are mostly made of raw powder of medicinal materials to make large honeyed pills. Not only is it inconvenient to take, the dosage is large, there are many impurities, it is easy to mildew, and the volatile components are easy to lose, and the quality is difficult to control. There are few research reports on the extraction of ingredients of Kushen Pills and the reform of dosage forms. The inventor proceeded from the perspective of the hierarchy and connection of various ingredients in the compound Chinese medicine, and the overall effect of the compound. , multi-channel, multi-link and multi-target, aiming to provide a new extraction process of Angelica flavescens, through the use of solid fermentation technology to pretreat Angelica and Sophora flavescens, and then combine the traditional water decoction extraction process to process the fermentation product, In order to obtain the extract product with stronger anti-inflammatory effect

Method used

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  • Technology for extracting Chinese angelica and lightyellow sophora root
  • Technology for extracting Chinese angelica and lightyellow sophora root
  • Technology for extracting Chinese angelica and lightyellow sophora root

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Take 200g angelica (passed through a 20-mesh sieve), 200g flavescens (passed through a 20-mesh sieve), 10g wheat bran and 2g calcium oxide, stir well, add 20g (ie 20ml) of water to moisten the medicinal materials, and pack the medicinal materials after fully stirring. Put it into a fermentation culture bag and seal it. Put the fermentation culture bag into a high-pressure steam sterilizer for sterilization, raise the sterilization pressure to 0.1MPa, and keep the pressure between 0.1-0.15MPa for 1.5h. After cooling down, take out the culture bag. To inoculate Coprinus comatus, the inoculation amount is 0.5wt%: take the test tube of Coprinus comatus female species, put the inoculation needle in the mouth of the test tube to cool for a while, then remove the aging bacterial classification on the surface of the female species, take a part and put it into a labeled culture bag, and quickly Seal it and put it away. Then the culture bags were placed in a 27°C incubator for ...

Embodiment 2

[0063] Take 250g angelica (through 20 mesh sieve), 250g sophora flavescens (pass through 20 mesh sieve), 12g wheat bran and 2g calcium oxide, stir well, add 30g (ie 30ml) water to moisten the medicinal material, mix well and pack the medicinal material Put it into a fermentation culture bag and seal it. Put the fermentation culture bag into a high-pressure steam sterilizer for sterilization, raise the sterilization pressure to 0.1MPa, and keep the pressure between 0.1-0.15MPa for 2 hours. After cooling down, take out the culture bag. To inoculate Coprinus comatus, the inoculum amount is 0.7wt%: get the test tube of Coprinus comatus female species, put the inoculation needle in the mouth of the test tube for a while, then remove the aging bacterial classification on the surface of the female species, get a part and put it into a labeled culture bag, and quickly Seal it and put it away. Then the culture bags were placed in a 25°C incubator for 28 days. Use the "double extract...

Embodiment 3

[0067] Take 300g angelica (passed through a 20-mesh sieve), 300g flavescens (passed through a 20-mesh sieve), 20g of wheat bran and 6g of calcium oxide, stir well, add 40g (ie 40ml) of water to moisten the medicinal material, and mix well. Put it into a fermentation culture bag and seal it. Put the fermentation culture bag into a high-pressure steam sterilizer for sterilization, raise the sterilization pressure to 0.1MPa, and keep the pressure between 0.1-0.15MPa for 2 hours. After cooling down, take out the culture bag. To inoculate Coprinus comatus, the inoculum amount is 1.0wt%: get the test tube of Coprinus comatus female species, put the inoculation needle in the mouth of the test tube to cool for a while, then remove the aging bacterial classification on the surface of the female species, get a part and put it into a labeled culture bag, and quickly Seal it and put it away. Then the culture bags were placed in a 29°C incubator for 25 days. Use the "double extraction m...

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Abstract

The invention belongs to the field of traditional Chinese medicines and discloses technology for extracting Chinese angelica and lightyellow sophora root. The extraction technology comprises the step of performing (1) solid fermentation treatment and (2) water extraction treatment on the prepared Chinese angelica and lightyellow sophora root according to a ratio in turn, wherein coprinus comatus is taken as a fermentation strain in the solid fermentation treatment. Compared with the extract obtained by common water extraction treatment, the obtained extract of the Chinese angelica and lightyellow sophora root has the characteristic of stronger anti-inflammatory effect, and is safe and reliable through toxicological test.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a compound extraction process of angelica flavescens. Background technique [0002] Acne and eczema are clinically common skin diseases that affect the quality of life and aesthetics of patients. Western medicine treats skin diseases such as acne and eczema with hormones, antibiotics or other anti-inflammatory and antibacterial drugs, which are prone to allergies, liver and kidney damage, pigmentation, and side effects such as rebound after drug withdrawal (see Wang Haisheng, etc. editors, Clinical New Drug Handbook [M ], Tianjin: Tianjin Science and Technology Publishing House, September, 2000, the first edition: 1,434.); And Angelica Kushen Pill is my country's first batch of non-prescription Chinese patent medicine, its effect is relaxed, and toxic side effect is little, and price is low, It is an ideal compound for the treatment of these skin diseases w...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12P1/02A61K36/489A61P17/10A61P17/00
Inventor 王英姿韩春超张超孙秀梅
Owner 王英姿