Equipment for dynamically simulating and testing biodegradability of medical magnesium alloy in vitro

Abstract

The invention discloses equipment for dynamically simulating and testing the biodegradability of a medical magnesium alloy in vitro. The equipment comprises a thermostatic bath, a liquid storage tank, a circulating pump, a flow meter, a test chamber, an upper-level sample loader, a pipette and a backflow tube, wherein the pipette and the backflow tube are arranged in the liquid storage tank respectively; the liquid storage tank is arranged in the thermostatic bath; the flow meter and the test chamber are vertically fixed respectively; the upper sample loader is hung in the test chamber by a chamber top cover of the test chamber; and the pipette is connected with an inlet of the circulating pump, an outlet of the circulating pump is connected with the inlet of the flow meter, the outlet ofthe flow meter is connected with an inlet tube of the test chamber, and an outlet tube of the test chamber is connected with the backflow tube by matched water pipes respectively to form a liquid medium circulation path. The equipment has the advantages of compact structure, convenience of use, high university and the like. By the equipment, the influence of medium flow rate, components, temperature, pH value and the like on medium corrodibility and material degradability can be quickly and accurately tested and evaluated, the research and development efficiency and quality can be obviously improved, and the research and development cost can be obviously reduced.

Description

technical field [0001] The invention belongs to the field of material performance testing technology and equipment, and relates to a device for dynamic simulation test and evaluation of material corrosion degradation performance in a fluid medium, especially suitable for biomedical materials / apparatus such as medical magnesium alloy and its medical equipment biodegradation In vitro dynamic simulation testing of performance. Background technique [0002] For materials serving in a liquid environment, such as medical devices implanted in the human body, ships in seawater, etc., the relative motion between them and the medium has a very important impact on their corrosion degradation behavior. Studies have shown that this relative movement can not only change the corrosion degradation rate of the material / device, but also change its corrosion degradation type and its mechanism. Therefore, simulating the actual service conditions, especially the relative movement between the en...

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Problems solved by technology

Although this method is simple and easy to implement, it has the following main disadvantages: 1) It ignores the important influence of the relative motion of the material / medium on the corrosion degradation behavior of the material except convection

The biomedical application of magnesium alloy is just around the corner, especially when it is used as a coronary stent, it will inevitably be sheared by flowing body fluids such as blood, tissue fluid, etc.; It is difficult to accurately predict the in vivo biodegradability of materials / devices, which greatly reduces its clinical reference value, thus losing the due significance of in vitro research

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