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Enrofloxacin soluble powder and preparation method and application thereof

A kind of enrofloxacin and soluble technology, which is applied in the new field of medicine, can solve the problems of poor sterilization effect and low enrofloxacin solubility, and achieve the effect of easy intake and absorption, stable cold and hot storage, and high concentration

Inactive Publication Date: 2011-05-04
QINGDAO VLAND BIOTECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The invention provides an enrofloxacin soluble powder and its preparation method and application, which can solve the problem in the prior art that the bactericidal effect is not good due to the low solubility of enrofloxacin in water

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A kind of enrofloxacin soluble powder is the mixture of enrofloxacin and sodium hydroxide, and its preparation method is as follows:

[0025] (1) Enrofloxacin and sodium hydroxide are pulverized respectively and passed through a 50-mesh sieve respectively;

[0026] (2) Put enrofloxacin and sodium hydroxide into the mixer at a mass ratio of 5: 1 and mix for 30 minutes;

[0027] (3) Packing.

Embodiment 2

[0029] A kind of enrofloxacin soluble powder is the mixture of enrofloxacin and potassium acetate, and its preparation method is as follows:

[0030] (1) Enrofloxacin and potassium acetate are pulverized respectively and passed through a 50-mesh sieve respectively;

[0031] (2) Enrofloxacin and potassium acetate were dropped into a mixer in a mass ratio of 3: 1 and mixed for 30 minutes;

[0032] (3) Packing.

Embodiment 3

[0034] A kind of enrofloxacin soluble powder is the mixture of enrofloxacin and potassium hydroxide, and its preparation method is as follows:

[0035] (1) Enrofloxacin and potassium hydroxide are pulverized respectively and passed through a 50 mesh sieve respectively;

[0036] (2) Enrofloxacin and potassium hydroxide were dropped into a mixer in a mass ratio of 3: 1 and mixed for 30 minutes;

[0037] (3) Packing.

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PUM

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Abstract

The invention provides enrofloxacin soluble powder and a preparation method and application thereof, and can solve the problem of poor sterilizing effect due to lower solubility of enrofloxacin in water in the prior art. A technical scheme is that: the enrofloxacin soluble powder is a mixture of enrofloxacin and solid inorganic alkali or organic alkali according to a weight ratio of (1-10):1. The invention also provides a preparation method and application of the enrofloxacin soluble powder. The invention solves the problem of low solubility of the enrofloxacin in the water, and overcomes the defect of poor curative effect due to low enrofloxacin concentration caused by taking the medicine with water.

Description

technical field [0001] The invention belongs to the field of new medicine technology, in particular, relates to a soluble powder of enrofloxacin and its preparation method and application. Background technique [0002] Quinolones are a class of synthetic bactericidal antibacterial drugs with broad antibacterial spectrum and strong antibacterial activity. At present, the third-generation products-fluoroquinolones are widely used, such as ciprofloxacin, enrofloxacin, ofloxacin, norfloxacin, pefloxacin, etc. Among them, enrofloxacin, as an animal-specific antibacterial drug, has attracted much attention from the veterinary field. It was successfully developed in my country in 1993 and has been widely used in veterinary clinics. Enrofloxacin has the characteristics of broad antibacterial spectrum, strong bactericidal power, rapid action, wide distribution in the body and no cross-resistance between other antibiotics, etc. It can prevent and treat bacterial infections and mycop...

Claims

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Application Information

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IPC IPC(8): A61K9/14A61K31/496A61K47/12A61K47/26A61K47/04A61P31/04
Inventor 林扬郝智慧贾德强刘元元张瑞丽
Owner QINGDAO VLAND BIOTECH INC
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