Method for producing liposome and method for dissolving cholesterol

Abstract

Disclosed is a method for producing a liposome, which comprises: a first mixing step wherein one or more lipids are mixed with an aqueous solution containing a water-miscible organic solvent; a heating step wherein the mixture obtained by mixing the lipids with the aqueous solution is heated to a temperature at which the lipids are dissolved in the aqueous solution; and a cooling step following the heating step, wherein the resulting mixture is cooled down to a temperature at which a liposome is produced. Uniform-sized liposomes having a high encapsulation rate can be easily obtained by the method.

Description

Technical field [0001] The present invention involves the preparation method of liposome and cholesterol dissolution. Background technique [0002] Liposy is formed by lipid molecules, which is almost wrapped in a layer of lipid bipomatte layer.The lipid molecules have hydrophilic bases with hydrophilicity, and the hydrocariac -based hydrocariacity located on the other side of it. When contacting water, the bipar layer will form.And the inside wrapped in the bipoor layer, the liposuoplastment forms spherical and minimizes the liposuoplasty to the interior of the layer of the biomolecular layer. [0003] The biopolin layer that forms a liposcope is similar to the cell membrane that constitutes the organism, so it is easily accepted by the organism of the organism.In recent years, the use of the above nature, the liposome as the drug transmission system (DRUG DELIVERY SYSTEM: DDS) is highly dazzling.Pharmaceutical parts.As other purposes, for example, the liposuction as a cosmetics...

AI Technical Summary

Problems solved by technology

[0008] However, the above-mentioned existing preparation method and the liposome obtained by the preparation method have the following problems: the particle size of the liposome is not uniform, or it is difficult to prepare liposomes with a uniform particle size

Images