Method for extracting silymarin from milk thistle seed coat

A technology of silymarin and silymarin, which is applied in the field of silymarin extraction, can solve the problems of crude silymarin with many impurities, low silymarin content, and large consumption of organic solvents, and achieve the effects of eliminating potential safety hazards, reducing weight, and reducing production costs

Inactive Publication Date: 2011-10-19
邸凤阁
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because milk thistle seeds contain a lot of impurities such as fat and starch, the extracted crude silymarin has a lot of impurities and must be post-treated, that is, degreasing with soybean solvent o...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] 1. Clean the milk thistle seeds;

[0008] 2. Use a sheller (TFKH1500 sunflower shelling and sorting unit produced by Jinzhou Qiaopai Machinery Co., Ltd.) to shell the milk thistle seeds, and obtain the seed coat and kernel of milk thistle respectively;

[0009] 3. Use solvent (acetone, ethanol or hexyl acetate, etc.) to extract the silymarin seed coat;

[0010] 4. Concentrate and recover the solvent to obtain silymarin;

[0011] 5. Drying under reduced pressure and crushing.

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PUM

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Abstract

The invention provides a method for extracting silymarin from milk thistle seed coat. The objective of the invention is to solve the following problem in the prior art: the extraction of silymarin from milk thistle exotesta uses the integral body of milk thistle as the raw material, and therefore the extracted coarse silymarin contains considerable impurities and has to be refined; the process of refinement is cumbersome and consumes considerable organic solvents. The method provided in the invention comprises the following steps: cleaning milk thistle seeds; decorticating the milk thistle seeds with a decorticator so as to obtain milk thistle seed coats and seed kernels respectively; carrying out extraction on the milk thistle seed coats with a solvent; recovering the solvent by condensation so as to obtain silymarin. According to the invention, silymarin extracted from milk thistle seed coats has a quality far surpassing the international standard.

Description

technical field [0001] The invention relates to a method for extracting silymarin, in particular to a method for extracting silymarin from the seed coat of milk thistle. Background technique [0002] Milk thistle (or called milk thistle) is the seed of a natural plant, which contains silymarin. The silymarin extracted from milk thistle can rapidly improve indicators such as albumin and globulin coefficient, thrombin element, and alanine aminotransferase , has a good curative effect on acute and chronic hepatitis, liver cirrhosis, fatty liver, etc. Milk thistle consists of a seed coat enclosing a kernel. The current method for extracting silymarin from milk thistle is to use the whole milk thistle (including the seed coat and seed kernel) as the raw material, and sequentially extract oil from the whole milk thistle, crush it, and add a solvent to obtain crude silymarin. Because milk thistle seeds contain a lot of impurities such as fat and starch, the extracted crude silyma...

Claims

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Application Information

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IPC IPC(8): C07D407/04
Inventor 邸凤阁
Owner 邸凤阁
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