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Compound nifedipine ointment and application thereof

A nifedipine and ointment technology, applied in the field of compound nifedipine ointment, can solve the problems of long wound healing time, cardiovascular and cerebrovascular accidents, affecting the operation effect, etc., so as to shorten the wound healing time, relieve pain and reduce excitability. Effect

Inactive Publication Date: 2012-01-25
张延祥 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional treatment of hemorrhoids generally adopts surgical treatment of western medicine. The purpose of surgical treatment is to remove the hemorrhoids or use mechanical methods such as suturing to embolize or collapse them. Although the therapeutic effect is relatively obvious, the postoperative pain is severe and the wound healing takes a long time , not only can cause many complications such as difficulty in defecation, urinary retention, etc., but also can produce a series of pathophysiological changes, making the patient emotionally tense, short of breath, rapid heart rate, elevated blood pressure, and severe cases can lead to cardiovascular and cerebrovascular accidents, directly affecting the to the effect of surgery

Method used

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  • Compound nifedipine ointment and application thereof
  • Compound nifedipine ointment and application thereof
  • Compound nifedipine ointment and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0041] Embodiment 1: compound nifedipine ointment, this ointment is mainly made according to conventional preparation process by the raw material of following parts by weight: first 25 parts of Coptis Rhizoma, 20 parts of Rhizoma Rhizoma Radix, 10 parts of Radix Astragali, 5 parts of Ganoderma lucidum, 5 parts of Safflower , 5 parts of Danshen, 15 parts of Angelica dahurica, 20 parts of angelica, 10 parts of frankincense, 10 parts of myrrh, 25 parts of scutellaria baicalensis, 25 parts of Cortex Phellodendri, and 450 parts of petrolatum to make ointment, and then add 1g of nifedipine to every 100g of ointment to make the finished product ; This ointment also includes conventional adjuvants or excipients for making ointment. The ointment is used for postoperative anal surgery, and is characterized in that it is used for postoperative recovery treatment of mixed hemorrhoids and other hemorrhoids. It can not only effectively relieve postoperative anal pain, but also effectively pr...

Embodiment 2

[0043] Embodiment 2: compound nifedipine ointment, this ointment is mainly made according to the conventional preparation process by the raw material of following parts by weight: first 5 parts of Coptis Rhizoma, 20 parts of Rhizoma Rhizoma Radix, 10 parts of Radix Astragali, 25 parts of Ganoderma lucidum, 20 parts of Safflower , 30 parts of Danshen, 15 parts of Angelica dahurica, 20 parts of angelica, 20 parts of frankincense, 20 parts of myrrh, 10 parts of skullcap, 5 parts of Cortex Phellodendri, 200 parts of petrolatum, and then add 0.8g of nifedipine per 100g of ointment. Finished product; this ointment also includes conventional auxiliary materials or excipients for making ointment. The ointment is used for postoperative anal surgery, and is characterized in that it is used for postoperative recovery treatment of mixed hemorrhoids and other hemorrhoids. It can not only effectively relieve postoperative anal pain, but also effectively promote wound healing.

[0044] How t...

Embodiment 3

[0045] Embodiment 3: compound nifedipine ointment, this ointment is mainly made according to the conventional preparation process by the raw material of following parts by weight: first 5 parts of Coptis Rhizoma, 15 parts of Rhizoma Rhizoma Radix, 20 parts of Radix Astragali, 10 parts of Ganoderma lucidum, 5 parts of Safflower , 25 parts of Danshen, 10 parts of Angelica dahurica, 20 parts of angelica, 15 parts of frankincense, 15 parts of myrrh, 20 parts of scutellaria baicalensis, 5 parts of Cortex Phellodendri, 350 parts of petrolatum, and then add 0.6g of nifedipine per 100g of ointment. Finished product; this ointment also includes conventional auxiliary materials or excipients for making ointment. The ointment is used for postoperative anal surgery, and is characterized in that it is used for postoperative recovery treatment of mixed hemorrhoids and other hemorrhoids. It can not only effectively relieve postoperative anal pain, but also effectively promote wound healing. ...

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Abstract

The invention discloses a compound nifedipine ointment and application thereof. The ointment is mainly prepared from the following raw materials in parts by weight according to the conventional preparation process: 5-25 parts of coptis root, 5-20 parts of rhizoma corydalis, 10-35 parts of astragalus, 5-25 parts of lucid ganoderma, 5-20 parts of safflower, 5-30 parts of red-rooted salvia root, 5-30 parts of dahurian angelica root, 5-25 parts of Chinese angelica, 5-20 parts of frankincense, 5-20 parts of myrrh, 5-25 parts of baikal skullcap root, 5-25 parts of amur corktree bark and 150-450 parts of vaseline. And a finished compound nifedipine ointment is obtained by adding 0.2-1.2 grams of nifedipine into every 100 grams of ointment. The ointment has a very ideal treating effect on anus pain after anus surgery, and particularly mixed hemorrhoid surgery.

Description

technical field [0001] The invention relates to a compound nifedipine ointment and the use of the medicine for treating anal pain after anal surgery, especially mixed hemorrhoids and other hemorrhoids, and for promoting wound healing, belonging to the technical field of medicines. Background technique [0002] Hemorrhoids are the most common anorectal disease. It can occur at any age, but the incidence increases with age. Pathological changes or displacement of the supporting structure of the anal cushion, venous plexus, and arterial anastomotic branches are internal hemorrhoids; pathological expansion or thrombosis of the subcutaneous venous plexus distal to the dentate line is external hemorrhoids; internal hemorrhoids pass through The abundant anastomotic branches of the venous plexus and the corresponding external hemorrhoids merged into a mixed hemorrhoid. Conventional methods of treating hemorrhoids generally adopt Western medicine surgical treatment. The purpose of ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/06A61P1/00A61P17/02A61P29/00A61K31/4422
Inventor 张延祥廖秀军杨关根
Owner 张延祥
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