Method for extracting liquiritin from liquorice

Abstract

The invention discloses a method for extracting liquiritin from liquorice, and the method comprises the following steps: (1) crushing the liquorice, extracting with deionized water and filtering to get liquiritin crude extract solution; and (2) mixing the liquiritin crude extract solution with a resin column, and performing elution, separation, purification and recrystallization. The liquiritin extracted by the method is a natural extract which is high in purity and low in cost, the production efficiency is high and the quality is stable and controllable.

Description

technical field

[0001] The invention belongs to a method for extracting and purifying liquiritin, in particular to a method for extracting liquiritin from licorice. Background technique

[0002] Licorice is the dried roots and rhizomes of Glycyrrhiza uralensis Fisch., G. inflata Bata1., and G. glabra L. of the leguminous plants Glycyrrhiza uralensis Fisch. Clearing heat and detoxifying, eliminating phlegm and relieving cough, relieving spasm and relieving pain, and harmonizing the effects of various medicines. The flavonoids in licorice have a variety of biological activities. In addition to anti-inflammatory, antibacterial, and anti-allergic effects, they also have obvious effects on anti-oxidation, anti-cancer, anti-cancer, and anti-tumor. Modern pharmacological studies have shown that liquiritin, isoliquiritin, liquiritigenin and isoliquiritigenin are the main active ingredients of licorice flavonoids.

[0003] Liquiritin is an isomer of isoliquiritin, white crystal, mo...