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Preparation method of cooked panax notoginseng extract and total ripe panax notoginseng saponins

A technology for cooking Panax notoginseng and extracts, which can be applied to medical preparations, pharmaceutical formulations, plant raw materials and other directions containing active ingredients, and can solve the problem of inconsistent conversion degree of saponin components, uneven distribution of moisture and heat, and increase the time required for steaming. and other problems, to achieve the effect of easy operation and large-scale production, easy product quality, and reduced energy consumption

Inactive Publication Date: 2012-04-18
KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The steaming method in the prior art uses dry notoginseng or notoginseng powder for steaming. In the steaming process, the dried raw materials must be soaked with water, which greatly increases the time required for steaming, and thus consumes more energy.
Moreover, due to the gradual asynchronous infiltration of moisture during the steaming process, the moisture and heat distribution inside and outside the raw materials are not uniform, so that the conversion degree of saponin components is also inconsistent, and the product quality is not easy to stabilize.
When using Panax notoginseng powder for steaming, since Panax notoginseng contains a lot of starch, the surface is prone to gelatinization, which prevents further penetration of water vapor into the interior, which not only prolongs the steaming time, increases energy consumption, but also aggravates uneven heating , the problem that product quality is not easy to control

Method used

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  • Preparation method of cooked panax notoginseng extract and total ripe panax notoginseng saponins
  • Preparation method of cooked panax notoginseng extract and total ripe panax notoginseng saponins
  • Preparation method of cooked panax notoginseng extract and total ripe panax notoginseng saponins

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Embodiment 1

[0017] One, the preparation method of cooked Panax notoginseng extract and cooked Panax notoginseng total saponins extract of the present invention:

[0018] 1. The preparation method of cooked Panax notoginseng extract:

[0019] The plant raw material used to prepare the cooked Panax notoginseng extract is the fresh or dried whole root or various underground parts of Panax notoginseng (Burk.) F.H.Chen of Araliaceae, including rhizomes (commonly known as scissors) , reed head), main root (commonly known as head), branch root (commonly known as tendon, large tendon) and fibrous roots and the above-mentioned different parts mixed in various proportions.

[0020] The concrete steps that the present invention prepares cooked Panax notoginseng extract are as follows:

[0021] Raw Panax notoginseng crude extract preparation: dry or fresh underground part of Panax notoginseng is mechanically crushed to a certain particle size. Using ethanol or methanol or different concentrations o...

Embodiment 2

[0044] Preparation of cooked Panax notoginseng extract:

[0045] Take 5 kg of dry root of Panax notoginseng and crush it, extract 3 times with 70% ethanol under reflux at 80°C, concentrate and distill off the alcohol to obtain about 2 L of crude extract.

[0046] The crude extract of notoginseng was placed in a 5L glass triangular flask and steamed in an autoclave at 120°C for 8 hours.

[0047] After the liquid is cooled, the concentrated liquid is placed in a freeze dryer and freeze-dried to obtain 720 g of cooked Panax notoginseng extract with complete conversion of saponins.

Embodiment 3

[0049] Preparation of cooked Panax notoginseng extract:

[0050] Take 5 kg of dried notoginseng, crush it, extract by cold immersion in 70% methanol three times, concentrate and evaporate to remove alcohol, and obtain about 1.3 kg of brown-black notoginseng extract.

[0051] The notoginseng extract was placed in a white enamel dish and steamed in an autoclave at 100°C for 6 hours.

[0052] After the liquid was cooled, the concentrated liquid was placed in a freeze dryer and freeze-dried to obtain 764 g of the Panax notoginseng extract with complete conversion of cooked saponins.

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Abstract

The invention provides a preparation method of cooked panax notoginseng extract and total ripe panax notoginseng saponins, which is different from the prior art. The preparation method is characterized in that the raw panax notoginseng extract is steamed to obtain the cooked panax notoginseng extract; since the extract is in the state of aqueous solution, the structure conversion of saponin is beneficial, the heat conduction is faster, the heating is more uniform in steaming, the conversion of the saponin constituents is consistent, simultaneously the steaming time is shortened, and the energy consumption is reduced. In addition, the concentrated panax notoginseng extract is used for steaming, so that the volume of the steamed raw material is greatly reduced, the simplification of steaming equipment is beneficial, the production cost is reduced, simultaneously the operation is convenient, the preparation process is simple and easy, the production cycle is short, and the on-scale preparation and the industrial production are easy. According to the cooked panax notoginseng extract and the total ripe panax notoginseng saponins produced by the method, the chemical compositions are completely consistent to those of products prepared by the existing steaming method, the quality of the products is easy to control, and the standardization of the production is easy to realize.

Description

Technical field: [0001] The invention belongs to the field of medicines, and in particular relates to a preparation method of cooked notoginseng extract and a preparation method of cooked notoginseng total saponins. Background technique: [0002] Panax notoginseng (Burk.) F.H.Chen, also known as Tianqi, Jinbuhuan, etc., is a plant of the genus Ginseng in the Araliaceae family and is a famous precious Chinese medicinal material in my country. Panax notoginseng is an important medicine for hemorrhage in traditional Chinese medicine. It is used for hemorrhagic diseases such as internal and external injuries, and has the effect of nourishing blood. Radix Notoginseng has always been said as "raw and cooked tonic". Raw Radix Notoginseng is used for dispelling blood stasis, stopping bleeding, reducing swelling and relieving pain. Cooked Panax notoginseng has the effect of nourishing blood, invigorating blood circulation, strengthening deficiency. The processing of Panax notoginse...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258
Inventor 王东张颖君许敏朱宏涛杨崇仁
Owner KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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