The invention discloses a method for preparing a wine processed polygonatum kingianum decoction piece, and belongs to the technical field of traditional Chinese medicament processing. The method comprises the following steps: (1) selecting clean polygonatum kingianum, moistening the polygonatum kingianum by vapor, taking out the polygonatum kingianum, and slicing into thick slices for later use; (2) adding yellow rice wine into the thick slices in the step (1), uniformly stirring, steaming for 4-6 hours by vapor, collecting the steamed liquor, and uniformly stirring the steamed liquor with the polygonatum kingianum, steaming for 4-6 hours, collecting the steamed liquor and uniformly stirring with the polygonatum kingianum, and drying. The method follows the traditional preparation process, the polygonatum kingianum is moistened by vapor and sliced, and is uniformly mixed with the yellow rice wine for secondary vapor steaming, so that the steaming time can be effectively shortened, effective ingredient loss can be reduced, and the drug effect can be enhanced. The final product is uniform in quality and high in yield; and the preparation method is simple and low in cost and is suitable for large-scale industrial production, wherein polygonatum kingianum moistening by vapor is performed at a temperature of 110-120 DEG C and vapor pressure of 0.13-0.17MPa, the subsequent steaming time can be shortened, and loss of phlegm containing polygahatous polysaccharides can be reduced.