Compound amino acid injecta, and preparation method and detection method thereof

A compound amino acid, injection technology, applied in measuring devices, pharmaceutical formulations, color/spectral property measurement, etc., can solve the problems of complex structure, damage, and complicated operation of the instrument
CN102440989AActive Publication Date: 2012-05-09SICHUAN KELUN PHARMA RES INST CO LTD

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SICHUAN KELUN PHARMA RES INST CO LTD
Publication Date
2012-05-09

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Abstract

The invention discloses compound amino acid injecta, which contains arginine hydrochloride, histidine monohydrochloride, leucine, isoleucine, lysine hydrochloride and the like; meanwhile, the invention further discloses a preparation method of the compound amino acid injecta (18AA); in the event of ensuring the product quality, the compound amino acid injecta has the characteristics of saving energy and enhancing efficacy; by means of repetitive verification on precision, detection limit, quantitation limit, linear range and the like, a simple, convenient, rapid and reliable method with cleaning verification is ensured; furthermore, the residual quantity of antioxygen, namely sodium hydrogensulfite, in the compound amino acid injecta and sulphate ion generated by degrading sodium hydrogensulfite are detected according to an ion chromatography principle, thus, the amount of the antioxygen charged in the raw material proportioning can be accurately measured, and the stability of the raw material proportioning process is judged according to the measurement result; and a detection method of the compound amino acid injecta provided by the invention is an online derivative amino acid content measuring method, the speed is rapid, and the method is applied to large-scale detection.
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Description

technical field

[0001] The invention relates to an injection and a preparation method and a detection method thereof, in particular to a compound amino acid injection and a preparation method and a detection method thereof. Background technique

[0002] Compound Amino Acid Injection (18AA) is an amino acid infusion. Under the condition of sufficient energy supply, it participates in the synthesis and metabolism of protein, obtains positive nitrogen balance, and generates enzymes, hormones, antibodies and structural proteins, promotes tissue healing and restores normal physiological functions It is mainly suitable for patients with protein deficiency of total parenteral nutrition and severe protein loss caused by various reasons such as surgery and burns.

[0003] At present, the production process of compound amino acid injection (18AA) is mostly based on the solubility, and the intolerant amino acid is injected first, and then the soluble amino acid is injected after it dis...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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