Guide plates and flat type biological reactor using same and arrangement method

A technology of bioreactors and deflectors, applied in specific-purpose bioreactors/fermenters, biochemical equipment and methods, combinations of bioreactors/fermenters, etc., which can solve the problem of insufficient mixing in airlift bioreactors Uniformity, affecting the growth of organisms in the reactor, excessive circulation of the culture medium, etc., to improve the efficiency of light energy utilization, increase the chance of mass transfer between gas and liquid, and promote the effect of radial mixing

Active Publication Date: 2012-06-13
TAICANG CENTURY PORT GARMENT CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Airlift bioreactors are widely used in plant cell culture and fermentation industry. According to different aeration positions, they are divided into two types: internal circulation type and external circulation type. Driven by gas, the fluidity of the reactor is higher than that of other biological reactions. The airlift bioreactor is more uniform, as the liquid carries the air bubbles and circulates in the reactor, good gas-liquid mixing can be achieved, but the airlift bioreactor is not uniform enough when cultivating organisms at a high density
In addition, when using this reactor to cultivate photosynthetic organisms, such as microalgae and photosynthetic bacteria, under specific aeration conditions, the mixing ability is limited, coupled with the mutual shielding between organisms, "photoinhibition" will occur when the reactor is close to the light area Phenomenon, while the area far away from the light appears "light limitation" phenomenon, which greatly affects the growth of organisms in the reactor
When the air volume is increased to enhance turbulent mixing, the circulation velocity of the culture medium will also increase accordingly in the reactor with straight deflectors or straight deflector cylinders commonly used at present, and at the same time there will be a strong Turbulent disturbance will adversely affect most of the algae and bacteria that are suitable for growth under low flow rate and small disturbance environmental conditions, thereby reducing the production capacity of the reactor
[0003] The current research on the development of biological and photobioreactors is mainly devoted to changing the structural parameters of the reactor's built-in deflector or deflector, such as the height-to-diameter ratio of the deflector, the installation position of the deflector, and the structure formed by the deflector. The cross-sectional area ratio of the descending zone and the rising zone is used to improve the gas-liquid mass transfer and mixing in the reactor, but these optimization methods have little effect on the mixing of photosynthetic organisms in the light zone, especially the radial mixing in the light direction
At the same time, it does not solve the problem of excessive circulation flow rate of culture medium caused by increasing ventilation.

Method used

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  • Guide plates and flat type biological reactor using same and arrangement method
  • Guide plates and flat type biological reactor using same and arrangement method
  • Guide plates and flat type biological reactor using same and arrangement method

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Embodiment Construction

[0050] The deflector of the present invention, the flat-plate bioreactor using the deflector and the setting method are described in detail below in conjunction with the embodiments and accompanying drawings.

[0051] The flow deflector of the flat-plate bioreactor of the present invention, the flow deflector is a wave-shaped structure flow deflector 11 with concave and convex. Such as figure 1 , figure 2 , image 3 , Figure 4 As shown, the wave structure is one of arc wave structure 2 , triangular wave structure 3 , trapezoidal wave structure 4 and rectangular wave structure 5 . The period between the peak point of the previous highest peak of the wave-shaped structure deflector 11 and the peak point of the next highest peak is one cycle, and the waves of the wave-shaped structure deflector 11 have 1.5 cycles to 50 cycles.

[0052] Such as Figure 5 ~ Figure 12 As shown, the flat-plate bioreactor with a wave-shaped structure deflector of the present invention includes...

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Abstract

The invention relates to guide plates and a flat type biological reactor using the same and an arrangement method. The guide plates are guide plates with wave-shaped structures. According to the flat type biological reactor with the guide plates with the wave-shaped structures, a pair of guide plates with the wave-shaped structures is arranged in a reactor tank body symmetrically, and an upper end opening and a lower end opening which are formed by the two guide plates with the wave-shaped structures are horn-shaped openings which are expanded outwards. The arrangement method for the guide plates comprises the following steps of: determining the ventilatory capacity or ventilating speed of the flat type biological reactor according to the demand of the growth of cultured organisms to obtain a ventilating ratio R, namely R is equal to V1 / V2, wherein V1 is the volume of gas introduced into the reactor for 1 minute, and V2 is the volume of an actual culture solution in a cylindrical biological reactor; and determining the wave periodicity and amplitude of the guide plates with the wave-shaped structures according to the obtained ventilating ratio, and arranging the guide plates in the reactor tank body. By the guide plates and the flat type biological reactor using the same and the arrangement method, the number of times of mixing liquid can be increased, the effect of mixing the culture solution in the reactor can be improved greatly, the utilization efficiency of light energy can be improved, and mass transfer between gas and liquid can be improved greatly.

Description

technical field [0001] The invention relates to an air-lift flat plate bioreactor. In particular, it relates to a deflector and the use of the deflector to realize the optimal flow rate, turbulent mixing and gas-liquid mass transfer conditions of the organisms cultivated in the reactor by controlling the cycle number and amplitude of the concave and convex of the deflector or the deflector cylinder. A flat-plate bioreactor with a flow plate and an installation method thereof. Background technique [0002] Airlift bioreactors are widely used in plant cell culture and fermentation industry. According to different aeration positions, they are divided into two types: internal circulation type and external circulation type. Driven by gas, the fluidity of the reactor is higher than that of other biological reactions. The airlift bioreactor is more uniform, and as the liquid carries the air bubbles to circulate in the reactor, good gas-liquid mixing can be achieved, but the airlif...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00C12M1/04
CPCC12M41/00C12M23/04C12M27/18
Inventor 尤学一王淋淋季民
Owner TAICANG CENTURY PORT GARMENT CO LTD
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