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Iodine disinfection liquid and preparation method thereof

A disinfectant, iodophor technology, applied in the fields of botanical equipment and methods, disinfectants, chemicals for biological control, etc., can solve the problems of easy sublimation, short duration of bactericidal effect, and high irritation.

Inactive Publication Date: 2012-07-11
昆明振华制药厂有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Iodine-containing preparations are very effective disinfectants, which can quickly kill bacterial propagules, bacterial spores, Mycobacterium tuberculosis, fungi and viruses, but general iodine-containing disinfectants are more irritating and poorly water-soluble , easy sublimation, coloring, and easy to be oxidized, the bactericidal effect lasts for a short time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] The weight proportion of the drug raw material of iodophor disinfectant is:

[0058] Povidone-iodine 50g

[0059] Potassium iodate 0.1g

[0060] Sodium dihydrogen phosphate 6.4g

[0061] Disodium hydrogen phosphate 1.9g

[0062] 10% sodium hydroxide appropriate amount (adjust the pH value to 5-6)

[0063] Purified water to 1000mL

[0064] Preparation:

[0065] 1) Concentrated preparation: Weigh the prescribed amount of sodium dihydrogen phosphate, disodium hydrogen phosphate and potassium iodate, dissolve in 800mL boiled purified water, sprinkle povidone-iodine on the surface of the solution after cooling, and keep it in the dark for 2- Let it dissolve by itself for 3 days;

[0066] 2) Dilute preparation: After povidone-iodine is completely dissolved, adjust the pH value to 5-6 with (mass concentration) 10% sodium hydroxide, add purified water to make 1000mL, stir for 15 minutes to mix evenly to obtain a disinfectant;

[0067] 3) After the disinfectant is filtere...

Embodiment 2

[0069] The weight proportion of the drug raw material of iodophor disinfectant is:

[0070] Povidone-iodine 40g

[0071] Potassium iodate 0.15g

[0072] Sodium dihydrogen phosphate 8g

[0073] Disodium hydrogen phosphate 3g

[0074] 10% sodium hydroxide appropriate amount (adjust the pH value to 5-6)

[0075] Purified water to 1000mL

[0076] The preparation method is the same as in Example 1.

Embodiment 3

[0078] The weight proportion of the drug raw material of iodophor disinfectant is:

[0079] Povidone-iodine 65g

[0080] Potassium iodate 0.05g

[0081] Sodium dihydrogen phosphate 4g

[0082] Disodium hydrogen phosphate 1g

[0083] 10% sodium hydroxide appropriate amount (adjust the pH value to 5-6)

[0084] Add purified water to 1000mL

[0085] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention discloses iodine disinfection liquid and a preparation method thereof. The iodine disinfection liquid comprises the following medical raw materials in proportion by weights: 4-65 g of povidone iodine, 0.05-0.15 g of potassium iodate, 4-8 g of sodium dihydrogen phosphate, 1-3 g of disodium hydrogen phosphate, suitable amount of 10% sodium hydroxide and purified water added to 1000 mL. The iodine disinfection liquid disclosed by the invention is suitable for skin disinfection and mucous membrane (oral cavity and the like) disinfection, disinfection of surgical hand washing and healthy hand washing, disinfection of fire burn and wound and disinfection of surfaces of common objects. The iodine disinfection liquid disclosed by the invention has the advantages of low skin irritation, low toxicity, action durability, safety, convenience and simpleness for use as well as steady quality.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a povidone-iodine disinfectant and a preparation method thereof. Background technique [0002] Iodine-containing preparations are very effective disinfectants, which can quickly kill bacterial propagules, bacterial spores, Mycobacterium tuberculosis, fungi and viruses, but general iodine-containing disinfectants are more irritating and poorly water-soluble , easy sublimation, coloring, and easy to be oxidized, the bactericidal effect lasts for a short time. Contents of the invention [0003] The object of the present invention is to provide a kind of disinfectant iodophor disinfectant with good disinfection effect, good safety and good stability and preparation method thereof. [0004] The weight proportion of the drug raw material of iodophor disinfectant solution of the present invention is: [0005] Povidone iodine 40~65g [0006] Potassium iodate 0.05~0.15g [0007] So...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N59/12A01P3/00A01P1/00
Inventor 李俊
Owner 昆明振华制药厂有限公司
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