Microvibration loading device for bone formation related cells

A loading device and micro-vibration technology, applied in the field of mechanical-biological experimental devices of biological cells, can solve problems such as inability to simulate, achieve good integration, reliable test basis, and improve the effect of treatment and repair

Inactive Publication Date: 2012-07-11
SICHUAN UNIV
View PDF4 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is currently no device that can simulate the microvibration environment of bone formation-related cells to analyze the effect of microvibration on the proliferation activity and functional state of bone formation-related cells at the interface.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Microvibration loading device for bone formation related cells
  • Microvibration loading device for bone formation related cells
  • Microvibration loading device for bone formation related cells

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0016] figure 1 , figure 2 As shown, a specific embodiment of the present invention is a micro-vibration loading device for cells related to bone formation, which consists of:

[0017] The vibration head 1A of the electromagnetic vibrator 1 is screwed to the bottom of the vibration chamber 2, and the vibration chamber 2 is provided with a micro-vibration box 3 containing cells related to bone formation; the outer wall of the chamber cover 2A of the vibration chamber 2 passes through the vibration chamber 2 The side positioning screw 2B on the wall is positioned on the vibration chamber 2; the electromagnetic exciter 1 is electrically connected to the excitation control device;

[0018] The specific composition of the excitation control device of this example is: the control signal output end of the single-chip microcomputer 41 is connected with the input end of the sine wave signal generator 42, and the output end of the sine wave signal generator 42 is connected with the el...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a microvibration loading device for bone formation related cells. According to the device, the excitation end of an electromagnetic vibration exciter is in threaded connection with the bottom of a vibration cavity, and a microvibration box in which the bone formation related cells are accommodated is arranged in the vibration cavity; the cavity cover of the vibration cavity is positioned on the vibration cavity through a side positioning screw; the electromagnetic vibration exciter is electrically connected with an excitation control device; according to the excitation device, a singlechip controls a sine wave signal generator, and a power amplifier drives the electromagnetic vibration exciter; and control parameters are input and displayed by a display and input circuit. The device can perform microvibration loading on the bone formation related cells, stimulate the microvibration environment of the bone formation related cells to analyze the influence of microvibration on the proliferation activity and the functional state of the bone formation related cells of an interface, provides accurate and reliable experimental basis for design, manufacturing and implanting of an implant, ensures that the implant can be combined with the bone interface well, and improves the effects of treating and repairing the bone interface.

Description

technical field [0001] The invention relates to a mechanical-biological experiment device for biological cells, in particular to a micro-vibration loading device for analyzing and studying the biological response of cells related to bone formation to micro-vibration in vitro. Background technique [0002] Fretting refers to the movement of two contact interfaces with minimal relative displacement when they are subjected to alternating loads. Micromotion is unavoidable between the implant and its bone interface in animals. For example, when the dental implant performs its function in the oral cavity, the dental implant-bone interface will undergo the alternating stress of mastication and produce micromotion. In addition to fretting wear and local fatigue damage similar to traditional materials, as biologically active bone tissue, the biological response caused by fretting at the cellular level also largely determines the comprehensive performance of its interface. In order t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C12M3/00
Inventor 于海洋高姗姗肖凌
Owner SICHUAN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap