Device for simultaneous measurement and recording of oxygen consumption dynamic change of small animal

A dynamic change and recording device technology, applied in diagnostic recording/measurement, medical science, sensors, etc., can solve the problems of time-consuming and labor-intensive determination of oxygen consumption indicators in small animals, large errors, etc., to achieve simple experiments, convenient data processing, and recording The effect of accurate data

Inactive Publication Date: 2012-07-18
INST OF HYGIENE & ENVIRONMENTAL MEDICINE PLA ACAD OF MILITARY MEDICAL
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] In order to solve the problems existing in the prior art, the present invention provides a device for synchronously measuring and recording the dynamic change of oxygen consumption of small animals, which solves the problems of time-consuming and laborious and large errors in the determination of oxygen consumption indicators of small animals in the prior art

Method used

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  • Device for simultaneous measurement and recording of oxygen consumption dynamic change of small animal
  • Device for simultaneous measurement and recording of oxygen consumption dynamic change of small animal
  • Device for simultaneous measurement and recording of oxygen consumption dynamic change of small animal

Examples

Experimental program
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Effect test

Embodiment 1

[0022] Such as figure 1 As shown, in the animal cabin 15, due to the continuous inhalation of oxygen by the animal 17, the carbon dioxide produced is absorbed by the soda lime in the absorbent bottle 16, so that the water column of the first water detector 13 flows towards the interior of the animal cabin 15, and is completely immersed under the physiological saline liquid surface. The shorter electrode in the two electrodes 14 of the liquid level relay 12 breaks away from the liquid surface to trigger the circuit of the liquid level relay 12, open the air intake valve controlling the automatic air intake device, and supply oxygen to the animal cabin 15 through the rubber tube 11; After the oxygen consumed by the animals is compensated, the air pressure in the animal cabin 15 will rise so that the water column of the water gauge 13 flows to the direction outside the animal cabin 15, and the two electrodes 14 of the liquid level relay 12 are all immersed under the physiological ...

Embodiment 2

[0031] This embodiment is another embodiment of the present invention. The difference from Embodiment 1 is that the compensated water directly enters the lower part of the animal cabin 9, and the animal cabin is divided into upper and lower parts, and a partition plate 12 with holes is arranged in the middle. There is an opening on its top of the animal cabin 9 to be connected with one end of the water manometer 7, and two electrodes 8 are placed at the other end to be connected with the automatic control system 6. Such as figure 2 As shown, in the animal cabin 9, due to the continuous inhalation of oxygen by the animals 10, the carbon dioxide produced is absorbed by the soda lime in the absorption bottle 11 in the animal cabin 9, so that the water column of the water manometer 7 flows towards the interior of the animal cabin 9, and all of them are immersed in the physiological The shorter one of the two electrodes 8 of the liquid level relay control system 6 under the brine ...

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Abstract

The invention discloses a device for simultaneous measurement and recording of oxygen consumption dynamic change of a small animal. The device comprises an animal chamber, an absorbent bottle is placed inside the animal chamber, an upper opening of the animal chamber is connected with a first water detection meter, two electrodes of the first water detection meter is connected with a first relaycontrol system, two ends of the first relay control system are respectively connected with a pure oxygen storage bottle and the animal chamber through rubber hoses, the upper opening of the pure oxygen storage bottle is connected with a second water detection meter, two electrodes of the second water detection meter is connected with a second relay control system, two ends of the second relay control system are respectively connected with the pure oxygen storage bottle and a water storage bottle through rubber hoses, the water storage bottle is placed on a scale, and the scale is connected with a computer through a data output line. The device disclosed by the invention establishes a set of gas-liquid combined and real-time recording device, has the advantages of multiple paths, automaticreal-time recording and accurate data recording, and can be used for automatic continuous measurement and record of the entire animal oxygen consumption and oxygen consumption rate of multiple models. The experiments are simple, efficient and accurate.

Description

technical field [0001] The invention relates to a medical experiment device, in particular to a device for synchronously measuring and recording the dynamic change of oxygen consumption of small animals. Background technique [0002] The determination of oxygen consumption index and the evaluation of hypoxia resistance ability of small animals are one of the important contents of drug screening and mechanism research of hypoxia tolerance. The determination of the oxygen consumption index of small animals is mainly based on the fact that the animals placed in a closed container absorb oxygen in the air and release carbon dioxide. The carbon dioxide is absorbed by an appropriate amount of soda lime as a carbon dioxide absorbent to reduce the pressure of the closed container, and then measure the externally compensated oxygen. , air or water quality to calculate animal oxygen consumption and oxygen consumption rate. Whether it is to measure the oxygen consumption of small anim...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00
Inventor 汪海段瑞峰崔文玉龙超良张艳芳王重郭剑南文考纪佳丽刘晓华张志清曾祥芝黄轲
Owner INST OF HYGIENE & ENVIRONMENTAL MEDICINE PLA ACAD OF MILITARY MEDICAL
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