Preparation and test method of magnesium sulfate dried piece

A technology of magnesium sulfate dry flakes and magnesium sulfate, applied in the medical field, can solve problems such as downtime maintenance, loss, liquid leakage, etc., and achieve the effect of preventing infection and ensuring safe use.

Active Publication Date: 2012-08-15
YULIN PHARMA LTDE XISHUANG BANNA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The production of magnesium sulfate wet compress tablets is subject to high requirements for core materials and packaging materials. If there is a problem with the quality of packaging materials, leakage will occur and cause major losses.
In addition, the production equipment belongs to special equipment with high cost and poor maneuverability. During the production process, it is often shut down for maintenance.
But along with the continuous deepening of research, the inventor finds out in practice: magnesium sulfate wet compress sheet is prone to mildew and moisture extravasation in production and storage, is not easy to store for a long time
In addition, since the wet compress is a water-containing product, the whole process of production is difficult to control pollution due to water-containing operations, and the product is heavy, transportation costs and operations are also complicated

Method used

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  • Preparation and test method of magnesium sulfate dried piece
  • Preparation and test method of magnesium sulfate dried piece

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] (1) Dissolve 330g of magnesium sulfate with an appropriate amount of purified water and set aside;

[0065] (2) Cut the non-woven fabric into an area and shape suitable for the size and shape of the affected area, and set aside;

[0066] (3) Soak the cut non-woven fabric in magnesium sulfate solution.

[0067] (4) Dry in a dryer at 100°C, and control the moisture content at ≤5%;

[0068] (5) Control every 10 square centimeters of MgSO in dry magnesium sulfate flakes 4 ·7H 2 O content in 0.33g±0.07;

[0069] (6) Put them in plastic boxes or plastic bags and seal them after sterilization;

[0070] (7) Use water to moisten to the state of no dripping, add about 0.1mL of water per square centimeter.

Embodiment 2

[0072] (1) Dissolve 380g of magnesium sulfate with an appropriate amount of purified water and set aside;

[0073] (2) Put the 120cm whole roll of non-woven fabric on the transmission shaft, soak it with the magnesium sulfate solution in the magnesium sulfate solution storage tank, and then pass the transmission shaft to the tunnel dryer for drying at 80 ° C, sterilized, and the moisture is controlled at ≤ 5%;

[0074] (3) Dry and sterilize the film-coated non-woven fabric, and cut it into an area and shape suitable for the size of the affected area;

[0075] (4) Dry the medical material soaked in the magnesium sulfate solution at 80°C for 20 minutes, and control the 4 ·7H 2 O content in 0.38g±0.07;

[0076] (6) Put them in plastic boxes or plastic bags and seal them after sterilization;

[0077] (7) Use water to moisten to the state of no dripping, add about 0.1mL of water per square centimeter.

Embodiment 3

[0079] (1) Dissolve 430g of magnesium sulfate with an appropriate amount of purified water and set aside;

[0080] (2) Cut the medical materials into an area and shape suitable for the size of the affected area and keep them for later use;

[0081] (3) Soak the cut medical materials in magnesium sulfate solution for 10 minutes;

[0082] (4) Dry the medical material soaked in the magnesium sulfate solution at 60°C for 40 minutes, and control the MgSO 4 ·7H 2 O content is 0.43g±0.07; moisture is controlled at ≤5%;

[0083] (5) Put them in plastic boxes or plastic bags and seal them after sterilization;

[0084] (6) Use water to moisten to the state of no dripping, add about 0.1mL of water per square centimeter.

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PUM

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Abstract

The invention discloses a preparation and a test method of a magnesium sulfate dried piece. The preparation comprises the steps of taking medical material as a carrier, drying the medical material fully soaked by magnesium sulfate at 60-100 DEG C, and controlling the water in the magnesium sulfate dried piece to be less than or equal to 10%; and controlling the content of MgSO4.7H2O to be 0.25g-0.50g / plus or minus 0.07 per 10 square centimetre of the magnesium sulfate dried piece. When the magnesium sulfate dried piece is applied, the magnesium sulfate dried piece is moistened by water, but no water is dropped (adding 1mL of water per 10 square centimetre). According to the preparation and test method of the magnesium sulfate dried piece, the quality control on the finished magnesium sulfate dried piece is effective, and the precision, the stability and the repeatability of the method are high, the quality of the product can be controlled effectively, and the stability and the consistency of the product quality can be ensured, so that the safety and the effectiveness of the product can be ensured.

Description

technical field [0001] The invention belongs to the field of medical technology, and relates to a medical auxiliary material for the prevention and treatment of swelling and pain caused by edema in local subcutaneous tissue, more specifically, a preparation and detection method of dry magnesium sulfate tablets with anti-inflammatory, swelling-relieving and pain-relieving effects. Background technique [0002] Over the years, non-corrosive and corrosive drugs or solutions have entered the surrounding tissues due to negligence in intravenous infusion, causing exudation and extravasation, resulting in swelling and pain in local subcutaneous tissue. In recent years, the use of chemotherapy drugs by malignant tumor patients often causes superficial phlebitis in different degrees, which brings great pain to the patients. At present, the commonly used method for treating swelling and pain of local subcutaneous tissue is magnesium sulfate aqueous solution and medical phlebitis. The ...

Claims

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Application Information

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IPC IPC(8): A61L15/18G01N21/79G01N13/04
Inventor 贾国平
Owner YULIN PHARMA LTDE XISHUANG BANNA
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