Chinese medicine composition with effect of reducing blood fat as well as preparation method and application thereof

A composition and blood lipid-lowering technology, which is applied in the direction of drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, can solve the problems of large side effects, large doses of liver damage and other symptoms, and achieve a fast onset effect

Active Publication Date: 2012-09-26
石洪波
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] Therefore, although the existing Western medicines have definite curative effects, they have large side effects, while Chinese medicines are used in large doses for treating hyperlipidemia and have no effect on treating liver damage and concurrent diseases.

Method used

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  • Chinese medicine composition with effect of reducing blood fat as well as preparation method and application thereof
  • Chinese medicine composition with effect of reducing blood fat as well as preparation method and application thereof
  • Chinese medicine composition with effect of reducing blood fat as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0116] Recipe: 10g of lotus leaf, 10g of baicalin, 10g of leaking reed, 11ml of milk thistle oil.

[0117] Preparation:

[0118] Weigh the medicinal materials of lotus leaf, scutellaria baicalensis, and leaking reed, add water and decoct 3 times, each time with 10 times the amount of water, and decoct for 1 hour each time (soak the medicinal materials for 2 hours before the first decoction). The three extracts were all filtered and combined, concentrated to 81ml for later use, called A liquid. Use a pipette to pipette 11ml of milk thistle oil and Tween-808ml into a dry mortar, grind in one direction quickly and non-stop for several minutes, add 15ml of liquid A, continue grinding in the same direction for several minutes, and then slowly add the remaining A liquid and grind it evenly to prepare an emulsion with a concentration of 0.41g crude drug / mL.

Embodiment 2

[0120] Recipe: 10g of lotus leaf, 20g of baicalin, 20g of leaking reed, 20ml of milk thistle oil.

[0121] Preparation:

[0122] Weigh the medicinal materials of lotus leaf, scutellaria baicalensis, and leaking reed, add water and decoct twice, each time with 12 times the amount of water, and decoct for 2 hours each time (soak the medicinal materials for 2 hours before the first decoction). The two extracts were filtered and combined, concentrated to 138ml, and used as liquid A for later use. Use a pipette to pipette 20ml of milk thistle oil and 10ml of Tween-80 into a dry mortar, grind in one direction quickly and non-stop for several minutes, add 30% of the volume of liquid A, continue grinding in the same direction for several minutes, and then Slowly add the remaining liquid A and grind evenly to obtain an emulsion. The obtained emulsion is prepared into granules by adding conventional pharmaceutically acceptable auxiliary materials according to conventional methods.

Embodiment 3

[0124] Recipe: 10g of lotus leaf, 50g of Scutellaria baicalensis, 10g of leaking reed, 33ml of milk thistle oil.

[0125] The preparation method is the same as in Example 1.

[0126] The obtained emulsion is compressed into tablets by adding conventional pharmaceutically acceptable auxiliary materials.

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PUM

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Abstract

The invention relates to a Chinese medicine composition with an effect of reducing blood fat as well as a preparation method and application thereof. The Chinese medicine composition is prepared from the following raw materials: lotus leaves, scutellaria baicalensis, uniflower swisscentaury root and silybum marianum oil at a weight ratio of (1-5):(1-5):(1-5); the ratio of the silybum marianum oil to the lotus leaves, the scutellaria baicalensis and the uniflower swisscentaury is 1:(2-4) ml/g; and the silybum marianum oil is fat extracted from silybum marianum seeds. The Chinese medicine composition with the effect of reducing blood fat has the remarkable effect of reducing the blood fat and concurrently treating liver injury, and is safe and quick in effectiveness.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition with hypolipidemic effect, a preparation method and application thereof. Background technique [0002] Currently used blood lipid regulating drugs mainly include the following categories: [0003] 1. Statins [0004] It is effective in lowering cholesterol levels in all types of hyperlipidemia, however, familial hypercholesterolemia lacks LDL receptors and thus is less effective in drug therapy. Despite their protective cholesterol-lowering effects, about a quarter of patients taking the drugs had coronary events. [0005] 2. Fibrates, or fibrates, methoxyaromatic acids, fibrates [0006] It can treat hypertriglyceridemia and cause a significant reduction in plasma triglyceride levels, but it cannot treat type I hyperlipidemia with elevated chylomicrons and normal VLDL levels. Gemfibrozil is particul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/62A61P1/16A61P3/06
Inventor 石洪波
Owner 石洪波
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