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Porous polymer monolith, method for its preparation and use thereof

A technology of porous polymers and uses, applied in the direction of chemical instruments and methods, preparation of test samples, analysis materials, etc., can solve problems such as not suitable for introduction, accelerated drying process, etc.

Active Publication Date: 2015-11-25
UNIVERSITY OF TASMANIA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, paper-based cellulose materials are not particularly suitable for accelerating the drying process, especially for blood plasma, and are not suitable for introducing specific functions for the extraction of selective components from blood

Method used

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  • Porous polymer monolith, method for its preparation and use thereof
  • Porous polymer monolith, method for its preparation and use thereof
  • Porous polymer monolith, method for its preparation and use thereof

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Embodiment Construction

[0077] In an attempt to identify alternative materials that offer properties that facilitate the drying and storage of biological fluids such as blood and plasma samples for future extraction and analysis; or that allow specific functions to be introduced into storage media In an attempt, it has now been found that a bodily fluid storage medium can be formed from a porous polymer monolith. Non-limiting specific embodiments of the invention are described below.

[0078] The present invention generally relates to the use of porous polymer monoliths as media for drying and storing body fluids, especially blood and plasma. Thus, the porous polymeric monoliths described in this application may provide a suitable medium for the DBS process as an alternative to the paper-based cellulose materials currently in use. In particular embodiments, the porous polymer monolith provides an improved medium for storing biological material for later analytical testing, such as storing blood or p...

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Abstract

The present invention generally relates to porous polymer monoliths. The present invention also relates to processes for the preparation of porous polymer monoliths, storage mediums formed from porous polymer monoliths and use thereof in the drying and storage of body fluids including blood and blood plasma samples.

Description

technical field [0001] The present invention generally relates to porous polymeric monoliths. The present invention also relates to methods for the preparation of porous polymer monoliths, storage media formed from porous polymer monoliths, and their use for drying and storing body fluids, including blood and plasma samples. Background technique [0002] The sampling technique known as dried blood spotting (DBS) was developed in 1963 by microbiologist Robert Guthrie. The sample collection process is simple and involves collecting a very small amount of blood from a small incision in the heel or finger. A drop of blood is then applied directly to the sampling paper and dried for future analyte extraction. DBS sampling is now a common and consistent practice for quantitative and qualitative screening of metabolic disorders in newborns (Edelbroek, P.M., J. van der Heijden, and L.M.L. Stolk, Dried Blood Spot Methods in Therapeutic Drug Monitoring: Methods, Assays, and Pitfalls...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01J20/282C08F279/06G01N1/36B01J20/26C08J9/26B01J20/285C08L33/10
CPCC08J9/142B01J20/261B01J20/264B01J20/267B01J20/28042B01J20/28057B01J20/28083B01J20/28085B01J20/285B01J39/20B01J41/14B01J2220/82C08F265/04C08J2207/10C08J2333/06C08J2333/14C08L33/066G01N1/2813G01N2001/2826C08F220/04
Inventor 保罗·雷蒙德·哈达德艾米丽·弗朗西丝·希尔德埃斯米·坎迪什马克·A·J·贝利斯
Owner UNIVERSITY OF TASMANIA