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Novel double-chamber transfusion bag for packing parenteral nutritional injection

A parenteral nutrition and infusion bag technology, applied in the field of medicine, can solve problems such as lack of mixing conditions, increased pollution, and inability to completely ensure that the liquid medicine is not polluted, and achieve the effect of reducing pollution risks and increasing labor intensity

Inactive Publication Date: 2012-11-07
LIAONING HAISCO PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The current total parenteral nutrition infusion generally pours different types of infusion into a large mixed bag. Generally, there are operating rooms in tertiary hospitals, which can reduce the chance of contamination, but cannot completely guarantee that the liquid will not be polluted. , but generally do not have the mixing conditions in primary hospitals, the probability of contamination will increase during preparation, there are medication safety problems, and the preparation process is cumbersome

Method used

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  • Novel double-chamber transfusion bag for packing parenteral nutritional injection
  • Novel double-chamber transfusion bag for packing parenteral nutritional injection
  • Novel double-chamber transfusion bag for packing parenteral nutritional injection

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0031] The preparation technology of double-chamber transfusion bag of the present invention

[0032]

[0033]

[0034]

[0035]*: In the three-layer co-extrusion film for infusion, the outer layer film is composed of polypropylene, styrene-ethylene-butylene copolymer; the middle layer film is composed of polypropylene / polyethylene, styrene-ethylene-butylene copolymer; The layer film is composed of polypropylene, styrene-ethylene-butylene copolymer.

[0036] **: The three-layer co-extrusion film for infusion is derived from the special film of PolyCine GmbH (registration number: Jinyaobaozi J20060015).

experiment example 1

[0037] Experimental Example 1 - Appearance Inspection

[0038] Take 10 each of Examples 1-32 of the present invention, respectively, and visually observe them in a bright place with natural light, all of which are transparent, smooth, and free of foreign matter visible to the naked eye. There are no cracks, fissures, pores, colored inclusions and foreign matter deposits at the mouth tube interface.

experiment example 2

[0039] Experimental Example 2 - Identification

[0040] (1) Microscopic characteristics: 10 samples of each of Examples 1-32 of the present invention were taken, cut into appropriate thicknesses, and observed under a microscope. The cross-section showed clear three layers.

[0041] (2) Actual welding strength: Take the examples 1-32 of the present invention and measure them respectively according to the method of composite bag in the heat sealing strength measurement method (YBB00122003). The average value of each heat sealing part is not less than 25N / 15mm.

[0042] (3) Insufficient weld strength: Take Examples 1-32 of the present invention and measure them according to the composite bag method in the heat seal strength measurement method (YBB00122003), and the average value of each heat seal part is (5N-20N) / 15mm.

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Abstract

The invention belongs to the technical field of medicine and specifically relates to a triple-extruded double-chamber transfusion bag. The novel double-chamber transfusion bag is made through heat sealing, strippable spacing is formed between two chambers through hot pressing, the spacing has a function of isolating liquid medicine in the two chambers during storage and transportation, and the spacing can be conveniently opened when applied a certain amount of outer force during usage, so that the two chambers are communicated and liquid medicine in the two chambers is mixed. The triple-extruded double-chamber transfusion bag avoids faulty mixing easily caused when common infusion solutions are mixed, problems of granules caused by puncturing, cross contamination and the like are reduced, and stability of transfusion is improved. The infusion solutions packed by the double-chamber transfusion bag meet the requirements of safe, quick and convenient transfusion treatment in clinics.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to a three-layer co-extruded double-chamber infusion bag for packaging parenteral nutrition products. Background technique [0002] Since the introduction of intravenous infusion in 1931, infusion therapy has become one of the most common and common clinical treatments. The packaging form of infusion solution has mainly gone through the following stages in the development: glass bottle infusion solution - plastic bottle infusion solution - PVC soft bag infusion solution - non-PVC soft bag infusion solution. The three-layer co-extruded double-chamber infusion bag is what is commonly referred to as a ready-to-use soft infusion bag. [0003] In order to ensure the tightness of the solder joints during sterilization and storage and transportation, and to be able to open them conveniently during use, the requirements for packaging materials, production equipment and processes are very ...

Claims

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Application Information

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IPC IPC(8): A61J1/10A61L2/04
Inventor 佐建锋冯卫张晓琳
Owner LIAONING HAISCO PHARMACEUTICAL CO LTD
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