Extraction method of periplaneta americana extract for treating peptic ulcer

A technology for digestive ulcers and Periplaneta americana, applied in the field of medicine, can solve the problems of different and immature, and achieve the effect of preventing hydrolysis, preventing corruption and deterioration, and shortening the process route

Active Publication Date: 2013-01-23
KUNMING SINOWAY NATURAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Although there are some disclosures about the extraction method of the American cockroach extract, the American cockroach contains many ingredients, and the ingredients obtained by different extraction methods are also different, and the obtained extracts also have different effects on differ...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The extracting method of the Periplaneta americana extract that is used for the treatment of peptic ulcer comprises the following steps:

[0028] A, pulverizing: the dry Periplaneta americana body of 200Kg is pulverized, crosses 24 mesh sieves, makes Periplaneta americana meal;

[0029] B, soak: step A gained Periplaneta americana coarse powder is soaked with the ethanol of concentration 95%, makes ethanol liquid level higher than coarse powder liquid level 5cm airtight preservation, makes coarse powder mixed solution;

[0030] C. Extraction: Put the coarse powder mixture obtained in step B into the extraction tank, and carry out reflux extraction for 3 times at a temperature of 70-85°C. When extracting the coarse powder mixture for the first time, add 1000Kg of ethanol with a concentration of 95% , the extraction time was 4 hours; after the second time, each extraction added 600Kg concentration of 95% ethanol, and the extraction time was 3 hours; the combined extracts ...

Embodiment 2

[0036] The extracting method of the Periplaneta americana extract that is used for the treatment of peptic ulcer comprises the following steps:

[0037] A, pulverizing: the dry Periplaneta americana body of 200Kg is pulverized, crosses 24 mesh sieves, makes Periplaneta americana meal;

[0038] B, soak: step A gained Periplaneta americana coarse powder is soaked with the ethanol of concentration 92%, makes ethanol liquid level higher than coarse powder liquid level 8cm airtight preservation, makes coarse powder mixed solution;

[0039] C. Extraction: Put the coarse powder mixture obtained in step B into the extraction tank, and carry out 4 times of reflux extraction at a temperature of 70 to 85°C. When the coarse powder mixture is extracted for the first time, 1000Kg of ethanol with a concentration of 92%, The extraction time is 5 hours; after the second time, 800Kg of ethanol with a concentration of 92% is added for each extraction, and the extraction time is 4 hours; the extr...

Embodiment 3

[0045] The extracting method of the Periplaneta americana extract that is used for the treatment of peptic ulcer comprises the following steps:

[0046] A, pulverizing: the dry Periplaneta americana body of 200Kg is pulverized, crosses 24 mesh sieves, makes Periplaneta americana meal;

[0047] B, soak: step A gained Periplaneta americana coarse powder is soaked with the ethanol of concentration 90%, makes ethanol liquid level higher than coarse powder liquid level 10cm airtight preservation, makes coarse powder mixed solution;

[0048] C. Extraction: Put the coarse powder mixture obtained in step B into the extraction tank, and carry out reflux extraction for 5 times at a temperature of 70 to 85°C. When the coarse powder mixture is extracted for the first time, 1600Kg of ethanol with a concentration of 90%, The extraction time is 6 hours; after the second time, 1200Kg of 90% ethanol is added for each extraction, and the extraction time is 5 hours; the extracts are combined and...

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PUM

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Abstract

The invention provides an extraction method of a periplaneta americana extract for treating peptic ulcer, comprising the following steps of:A, crushing, B, soaking, C, extracting, D, primarily concentrating, E, degreasing, and F, secondarily concentrating. According to th invention, extraction is carried out by using the method, lots of proteins contained in periplaneta Americana can be effectively removed, and the degreasing rate is high; and moreover, 90-95% ethanol is used for soaking a coarse powder, so that preservation time is prolonged, and the yield of specific active ingredients for treating peptic ulcer is increased. Due to reasonable control on each process parameter, hydrolysis of the active ingredients for treating peptic ulcer in the extract can be prevented, and the curative effect of the medicine can be improved. With the process disclosed by the invention, the extraction method is low in production cost and high in production efficiency. Clinically applicable preparations (tablets, capsules, mixture, oral liquid, pellets, dripping pills, spray, aerosol, gels and the like) can be prepared by taking the periplaneta americana extract obtained by the method disclosed by the invention and adding proper pharmaceutical auxiliary materials, and are used for (oral-administration or spray) treatment for peptic ulcer.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a method for extracting Periplaneta americana extract for treating peptic ulcer. Background technique [0002] The American cockroach (Periplaneta americana) is the largest insect in the cockroach family. The adult body is 29-35 mm long, reddish brown, and the wings are longer than the end of the abdomen. The antennae are very long, and there is a large butterfly-shaped brown stripe in the middle of the pronotum, and the rear edge of the stripe has a complete yellow stripe. It is native to South America , a wide range of eating habits, like sugar and starch, polluted food. [0003] Periplaneta americana is a traditional Chinese medicinal material, and adults are used as medicine. It is cold in nature, salty in taste, poisonous, pungent, and has the functions of dispelling blood stasis, eliminating stagnation, detoxifying, diuresis, and reducing swelling. Modern research has f...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61P1/04
Inventor 何道峰郝振平
Owner KUNMING SINOWAY NATURAL PHARMA
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