48results about How to "Improve the yield of active ingredients" patented technology

The invention discloses a method of extracting rose essential oil and rose pure dew, using the distillation technique in the water vapor. The method includes the steps: (1) the roses are fed into a distillation kettle; (2) deionized water is added to the distillation kettle; (3) non-iodine salt is added to the distillation kettle; (4) the coiled pipe is opened to supply steam and heat the distillation kettle; (5) the condenser is opened to supply cooled water; the cooled oil water is mixed with steam; (6) the oil water mixture cooled by the condenser is guided into an oil water separator for the oil water separation; (7) the water layer separated by the oil water separator flows back to the distillation kettle to have repeated distillation; when the repeated distillation is finished, the repeated flow valve is closed and the collector valve is opened to collect the water layer so that the rose pure dew is obtained; (8) when the oil and water are divided into layers, the oil water separator is opened to collect the water layer so that the rose essential oil is obtained; (9) water is released and the waste slag is discharged. The method of extracting the rose essential oil and the rose pure dew has the advantages of high stability of the products, high content of the active composition, simple operation, easy mastery and low production cost.

The invention provides a technological method of extracting and separating capsaicin, capsicum red pigment and capsicum oleoresin crude products from red pepper, which adopts the red pepper pulverized with a certain particle size as material and hydrous ethanol as extraction solvent, and three-stage extraction method for the preparation of the three extracts of capsaicin, capsicum oleoresin and capsicum red pigment separated in the extraction phase. The three extracts are respectively vacuum concentrated and distilled, and the crude products of capsaicin, capsicum red pigment and capsicum oleoresin can be gotten after the solvent recovery and solvent residue removal. The extracting and separating method separates the capsaicin, capsicum oleoresin and capsicum red pigment in the extraction phase by using the same extraction tank and solvent, avoids the trouble of separating the capsaicin and capsicum red pigment in the late workshop section, eliminates the alkali and acidification treatments or the separation craft of column chromatography, facilitates the improvement of the output ratio of capsicum red pigment and capsaicin. The technological method of extracting and separating capsaicin, capsicum red pigment and capsicum oleoresin crude products from red pepper has the advantages of simple technique, easy operation and control, less equipment investment, easy solvent recovery and reuse, low cost, short cycle, high yield of active ingredient, and better suitability for commercial and mass production.

The invention relates to an extraction and preparation method for licorice effective ingredients, mainly to a method for simultaneously extracting effective ingredients like glycyrrhizic acid, glycyrrhiza flavonoid and a licorice flavoring agent from licorice. The method comprises the following steps: with glycyrrhizic acid as a raw material, carrying out extraction so as to obtain licorice residue and extract liquid and subjecting the licorice residue to ethanol extraction so as to obtain a crude glycyrrhiza flavonoid product; removing impurities in the licorice extract liquid by using an ultrafiltration membrane device, carrying out concentration by using a nanofiltration membrane device, subjecting a nanofiltration membrane concentrate to acid precipitation and drying a precipitate so as to obtain glycyrrhizic acid; and subjecting a supernatant produced after acid precipitation to concentration with the nanofiltration membrane device and carrying out drying so as to obtain the licorice flavoring agent. The method adopts membrane separation technology for impurity removal and concentration of the extract liquid, so working conditions are mild, product purity and quality are guaranteed, and yield of licorice effective ingredients is high; the method has the advantages of simple production flow, low cost, small pollution, reusability of a nanofiltration membrane filtrate generated in production process, reduction in consumption of raw water and great decrease of waste water discharge.

The invention belongs to the technical field of healthcare food, and particularly relates to ficus hispida fruit compounded tea tablets capable of reducing the blood glucose and a preparation method for the ficus hispida fruit compounded tea tablets. The ficus hispida fruit compounded tea tablets are prepared from the following raw materials in parts by weight: 20 to 30 parts of green tea, 6 to 10 parts of an aquilaria sinensis fresh leaf, 3 to 9 parts of a ficus hispida fruit, 2 to 6 parts of immature psidium guajava, 0.4 to 1.2 parts of raw dark green tea, 2 to 4 parts of cordyceps militaris, 0.4 to 0.8 part of artificially cultured dendrobium officinale green shoot, 0.4 to 0.6 part of edible grade eurotium cristatum liquid, 0.2 to 0.4 part of saccharomyces cerevisiae liquid and 0.002 to 0.008 part of Pullulan. Processes comprise fixation, extraction, fermentation, mixing, pressing, drying under the reduced pressure, and packaging. The ficus hispida fruit compounded tea tablets have the characteristics of quick-acting reduction of the blood glucose, treatment of the diabetes mellitus, good flavor taste, convenience in taking and the like.

The invention relates to a preparation method for water-soluble seamin. The preparation method comprises the following steps: selecting sesame seed meal as a raw material; performing secondary enzymatic hydrolysis, water washing, solvent extraction, active carbon treatment, cyclodextrin inclusion, membrane separation and freeze drying technology to obtain a water-soluble sesamin product of which the sesamin content is not lower than 65 percent by weight and the sesamin recovery rate is higher than 95 percent. The method is simple and convenient in steps; moreover, the conventional method using a toxic reagent, namely, diethyl ether or n-hexane is abandoned, so that the finished product quality of the sesamin product is ensured well, the water-soluble sesamin product is obtained directly, and subsequent production and utilization of the sesamin product are facilitated well.

The invention discloses mint soda water and a production method thereof. The mint soda water is prepared by adding 1-20g of soda and 1-50g of mint extracts into every 1,000mL of purified water. The production method of the mint soda water comprises the following steps: 1, preparation of mint extracts; 2, preparation of the mint soda water. The mint extracts are prepared by water distillation extraction with water vapor; the mint soda water is prepared by the following steps: uniformly mixing soda and purified water in a blending pot, adding the mint extracts into mixed liquid, stirring at high speed for 10-15min, and sterilizing the mixture under a condition of 80-100 DEG C for 1-2min and pouring. No essence is added into the prepared mint soda water, so that the prepared mint soda water is refreshing and has good taste and comparatively good palatability; in addition, the mint soda water is suitable for long-term storage, no sediment or suspended solid is formed during storage period, and the product is strong in stability and high in nutritive value, therefore, the mint soda water is an anti-fatigue and anthypnotic excellent drink.

The invention discloses an ultrasonic negative pressure circulating extraction device used for extracting active components of natural products, mainly comprising a reflux evaporator, an ultrasonic generator, a vacuum pump, a low temperature cooling agent circulating pump, an infusion pump, an extraction flask and a collection flask, wherein, the vacuum pump can create a negative pressure state in the reflux evaporator to allow the collection flask which is connected with the reflux evaporator keep the negative pressure state, so as to allow the solvents to be benefit for the evaporation and condensation of the collected extract in the evaporator; the low temperature cooling agent circulating pump can allow the evaporator to keep low temperature inside, so as to allow the solvents vaporized to the evaporator to be subject to high efficient condensation and return to the extraction flask which is connected with the evaporator; and the infusion pump can continuously convey the feed liquid in the extraction flask in the ultrasonic generator to the collection flask to allow the feed liquid in the extraction flask to be continuously diluted by fresh solvents condensed by the evaporator, and the feed liquid extracted with ultrasonic assistance is continuously conveyed to the collection flask for the circulating of condensation. The invention has the advantages of combination of advantages of ultrasonic assistant extraction and reflux extraction, high extraction efficiency, and available extraction at normal temperature, and is especially suitable for extracting thermo sensitive components.

The invention provides an extraction method of a periplaneta americana extract for treating peptic ulcer, comprising the following steps of:A, crushing, B, soaking, C, extracting, D, primarily concentrating, E, degreasing, and F, secondarily concentrating. According to th invention, extraction is carried out by using the method, lots of proteins contained in periplaneta Americana can be effectively removed, and the degreasing rate is high; and moreover, 90-95% ethanol is used for soaking a coarse powder, so that preservation time is prolonged, and the yield of specific active ingredients for treating peptic ulcer is increased. Due to reasonable control on each process parameter, hydrolysis of the active ingredients for treating peptic ulcer in the extract can be prevented, and the curative effect of the medicine can be improved. With the process disclosed by the invention, the extraction method is low in production cost and high in production efficiency. Clinically applicable preparations (tablets, capsules, mixture, oral liquid, pellets, dripping pills, spray, aerosol, gels and the like) can be prepared by taking the periplaneta americana extract obtained by the method disclosed by the invention and adding proper pharmaceutical auxiliary materials, and are used for (oral-administration or spray) treatment for peptic ulcer.

The invention relates to a method for extracting effective components of plant in the separating project, wherein it uses internal gasifying effusion method to extract; the plant organism is wetted by the low-boiling point absorber, to make the extractive dissolvent whose temperature is higher than the boiling point of desorbent flow along the stable wetted material, to heat and gasify the desorbent inside the material without gasification, and the effective component will be gasified and brought outside the material to be taken away with flowing dissolvent. Compared with present extraction technique, the invention can reduce the extraction time more than 10 times, and the effective component yield can be improved 10-20%; compared with microwave strengthen extraction method, the invention has simple operation, while its extracted dissolvent less 20-50% then intermission method.

The invention discloses a Chinese medicinal material earthworm enzyme and peptide compound preparation and a preparation method thereof. The earthworm enzyme and peptide compound preparation is prepared by grinding Chinese medicinal herb plants into powder and mixing the powder with water and earthworms. In the method, the nerves of earthworms are suppressed by Chinese medicinal herbs instead of chemicals, so that a drastic stress reaction is not performed on the earthworms and clean active ingredients are slowly and gradually discharged from a body surface. Therefore, the problems of low yield of active ingredients, high product cost, poor product purity and the like in the prior art are solved.

The invention discloses a health care product capable of improving sleep. The health care product is prepared from the following raw materials: 1-50 parts of longan, 1-50 parts of tuber fleeceflower stem, 1-45 parts of spina date seed and 0.8-30 parts of turmeric. The health care product has the beneficial effects that the health care product is simple in formula and reasonable in compatibility and follows the principle of treatment based on syndrome differentiation in the traditional Chinese medicine science; the medicines in the formula supplement each other; animal experiments prove that the health care product has the obvious function of improving sleep, is nontoxic and harmless to human bodies, has the health care function of improving immunity and has high safety; the formula can be prepared into different dosage forms of health care products for improving sleep by utilizing the medically accepted conventional preparation methods of preparations, and easily achieves mass production.

The invention relates to the field of volatile oil extraction, and provides a volatile oil extraction and separation device and a volatile oil extraction and separation system. The volatile oil extraction and separation device includes an extraction tank, a condenser, a bubbling oil-water separator and a steam generator; the top of the extraction tank is connected with the condenser, and the condenser is connected with the bubbling oil-water separator; the bubbling oil-water separator comprises a cylinder body; the cylinder body is provided with a first collector connected with the cylinder body and located at the top of the cylinder body, a second collector located at the bottom of the cylinder body, a condensate inlet, a condensate outlet and a bubbling port, and the bubbling port is located between the condensate inlet and the condensate outlet; the condensate outlet is connected with the steam generator, and a discharge end of the steam generator is connected with the extraction tank. The volatile oil extraction and separation device can separate and collect volatile oil with small evaporation capacity, high viscosity and relative density close to 1, and has the advantages of high yield, high purity and good quality. In addition, the volatile oil extraction and separation system can extract, separate and collect volatile oil and has high yield.

The invention discloses a method for inducing hairy roots of anisodus acutangulus C.Y.Wu et C.Chen and mainly provides a technology for inducing the hairy roots of the anisodus acutangulus C.Y.Wu et C.Chen by agrobacterium rhizogene mediated transformation. The method particularly involves agrobacterium rhizogene activation, transformed bacterium liquid preparation, explant transformation, hairy root subculturing, PCR (polymerase chain reaction) detection of the hairy roots and the like. The method is capable of achieving industrialized production of tropane alkaloids by means of high-efficiency induction and large-scale culture of the hairy roots of the anisodus acutangulus C.Y.Wu et C.Chen, and is of great significance to sustainable use of the anisodus acutangulus C.Y.Wu et C.Chen as a rare medicinal plant source.

The invention belongs to the technical field of microbial extraction, and relates to equipment and a method for extracting vitamin K2 from microbial fermentation liquor. The equipment comprises a continuous dynamic countercurrent extractor and a medium-pressure preparative chromatography, the medium-pressure preparative chromatography comprises at least one chromatographic group, each chromatographic group comprises four chromatographic columns connected in parallel, each chromatographic column is independently provided with a feed port, an eluent inlet A, an eluent inlet B and an eluent inletC, the feed port is connected with an extracting solution outlet of the continuous dynamic countercurrent extractor, the eluent inlet A, the eluent inlet B and the eluent inlet C are respectively connected with an eluent source A, an eluent source B and an eluent source C, the opening and closing of the four material inlets are respectively and independently controlled by valves, and the valves of different chromatographic columns in the same chromatographic group are synchronously switched. By adopting the equipment provided by the invention, the purity and yield of the vitamin K2 can be improved, and the whole extraction process can completely realize continuous automatic operation.

The invention relates to an extraction process of andrographolide, which comprises the following steps: cleaning, drying and crushing a traditional Chinese medicine andrographis paniculata, adding an ethanol solution with the weight volume fraction of 85-95%, which is 10 times that of the traditional Chinese medicine andrographis paniculata, heating and extracting, decolorizing an extracting solution by using activated carbon, performing enzymolysis, filtering, performing vacuum concentration, and carrying out gradient elution by using ethanol solutions with different concentrations after exchanging and adsorbing by using a weakly polar or non-polar macroporous resin column, and finally passing the eluent through a membrane and recrystallizing to obtain the high-purity andrographolide crystal. The extraction process provided by the invention ensures the activity of the andrographolide and improves the purity of the obtained andrographolide, and has the advantages of low cost, simplicity in operation, mild reaction conditions and easiness in industrial production.

The invention mainly relates to a method for extracting and separating rosmarinic acid and ursolic acid from rosemary. The method comprises the following steps of: grinding the rosemary serving as a raw material, extracting, concentrating, performing column chromatographic separation, extracting, concentrating, crystallizing, recrystallizing, and thus obtaining the rosmarinic acid and the ursolic acid. The whole separation process has low requirements on environmental conditions and equipment, the rosmarinic acid and the ursolic acid have high yield, the shortest separation time, a simple operation method and high purity, and the raw material has the highest comprehensive utilization rate; in addition, the separation materials are readily available and cheap, and the separation operation process is simple and is easy to control; and crystallization and recrystallization are utilized, so that the method is high in purification efficiency and low in cost.

The invention provides a hericium erinaceus fruit body extract, a preparation method thereof, and an effervescent tablet containing the hericium erinaceus fruit body extract, and relates to the technical field of health food. The hericium erinaceus fruit body extract comprises a hericium erinaceus fruit body water extract obtained by performing 250-300 MPa ultra-high pressure water extraction on hericium erinaceus fruit bodies, and a hericium erinaceus fruit body alcohol extract obtained by performing 400-600 MPa ultra-high pressure alcohol extraction on the water-extracting filter residue ofthe hericium erinaceus fruit bodies. Compared with the existing hericium erinaceus extract, the hericium erinaceus fruit body extract has the advantages of high effective component yield and high purity of the extract. The hericium erinaceus fruit body extract can be used as a health raw material for preparing an effervescent tablet, and the prepared effervescent tablet has the effects of anti-oxidation, blood sugar reduction, immunity enhancement, anti-tumor, anti-aging, maintenance of the health of the gastrointestinal tract and the like, and meanwhile has good taste.

The invention discloses a Chinese medicinal material earthworm enzyme and peptide compound preparation and a preparation method thereof. The earthworm enzyme and peptide compound preparation is prepared by grinding Chinese medicinal herb plants into powder and mixing the powder with water and earthworms. In the method, the nerves of earthworms are suppressed by Chinese medicinal herbs instead of chemicals, so that a drastic stress reaction is not performed on the earthworms and clean active ingredients are slowly and gradually discharged from a body surface. Therefore, the problems of low yield of active ingredients, high product cost, poor product purity and the like in the prior art are solved.

The invention discloses a method for extracting ornithogalum caudatum saponin by combining an ultrasonic method with a reverse micelle technology. The method comprises the following steps: by taking ornithogalum caudatum as a raw material, ultrasonically extracting a crude saponin extract by using 60-90 percent of ethanol solution, drying by distillation, dissolving by using water, regulating the pH value to be 4.5-6.0, extracting by using a reverse micelle system formed by a mixed solvent of isooctane and n-caprylic alcohol and phosphate buffer, mixing the obtained reverse micelle phase with the phosphate buffer, respectively adding ethyl acetate and chloroform for extracting, drying by distillation, thereby obtaining the product. The method disclosed by the invention has the advantages of high selectivity, mild conditions and high yield and purity.

The invention discloses a preparation method and application of a soothing and repairing composition. The preparation method comprises the following steps: extracting components such as phenylpropanoid substances in oriental wormwood by taking water as an extraction solvent, removing poor-stability organic acid and part of flavonoid substances in a crude extract of the oriental wormwood by using aluminum oxide, then adsorbing phenylpropanoid in the extract by using macroporous adsorption resin, and finally desorbing by using an eluent containing quinoa saponin components, thereby obtaining the soothing and repairing composition. The soothing and repairing composition can be directly applied to the skin surface after being diluted, and the effects of soothing and repairing the skin are achieved.

The invention belongs to the field of food health, and discloses a preparation method of a multi-function gastrodia elata Bl. effervescent tablet. The preparation method includes the following steps: S1, removingnumb taste; S2, removing bitter taste; S3, performing crushing; S4, removing cell walls; S5, performing concentration; and S6, preparing the effervescent tablet. The purpose of the invention is to provide a preparation method of a multi-function gastrodia elata Bl. effervescent tablet, and to make gastrodia elata Bl. tablet being in high nutritive value preservation, easy to absorb, good in taste and convenient for people to carry and eat and not contain harmful chemical components; the effervescent tablet has good stability under strong light and high temperature and can be taken by brewing the tablet with water, so that the effervescent tablet is convenient for swallowing; and through the synergistic compatibility of vitamin C and a gastrodia elata Bl. extract, the effervescent tablet can have the effects of improving memory and calming the nerves.

The invention discloses Kefir-flavor fermented milk ferment powder and a preparation method thereof. The preparation method comprises the following steps that (1) reconstituted milk is blended, specifically, skimmed milk powder, white granulated sugar, yeast extract and water are mixed, and homogenized to obtain the reconstituted milk; (2) a culture medium is prepared, specifically, the reconstituted milk prepared in the step (1) is sterilized and cooled, and the sterilized reconstituted milk is taken as the culture medium; (3) bacteria are inoculated, specifically, a Kefir probiotic group is inoculated into the culture medium prepared in the step (2); 4) fermentation is carried out, specifically, the culture medium inoculated in the step (3) is fermented to form fermentation liquor; (5) blending is carried out, specifically, maltodextrin is added into the fermentation liquor prepared in the step (4), and stirred to prepare uniform blended liquor; and (6) spray drying is carried out, specifically, the spray drying is carried out on the blended liquid prepared in the step (5) to obtain the Kefir-flavor fermented milk ferment powder. The prepared Kefir-flavor fermented milk ferment powder can be supplied to the market for the Kefir-flavor fermented milk ferment powder required for preparing Kefir-flavor fermented milk food.

The invention discloses a wet smashing device, and belongs to the technical field of smashing equipment. The wet smashing device is characterized by comprising a smashing cylinder (4) which is vertically arranged and a smashing mechanism arranged in the smashing cylinder (4), the lower end of the smashing cylinder (4) is provided with a screening cover (14) for closing the lower end of the smashing cylinder (4), the screening cover (14) is a net cover which is formed through splicing of multiple rectangular blades (1401), the lower portion of the smashing mechanism is provided with a grindingpart, the grinding part is arranged on the upper side of the screening cover (14), and the grinding part and the screening cover (14) relatively rotate. The screening cover of the wet smashing devicecan screen the smashed materials, the materials meeting the granularity needs penetrate through the screening cover to be conveyed out, the grinding part and the screening cover are matched, the materials which do not meet the granularity need are re-ground, it is ensured that the ground materials are uniform in granularity, the subsequent material effective component extraction is improved, and the material effective component yield is improved.

The invention discloses an ultra-high pressure extraction method of honeysuckle, chrysanthemum indicum and mulberry leaves which is characterized in that 40-195 parts of honeysuckle, 35-180 parts of wild chrysanthemum and 20-120 of mulberry leaves are mixed and placed in an ultra-high pressure extraction tank; 60%-95% ethanol are added in an amount of 5 times the total weight of the above mixture;when the pressure reaches 100MPa-400MPa, the pressure is released immediately after holding for 8min, the extractive solution is taken out while filtering, the obtained filtrate is concentrated to 20%-30% of the original volume, and refrigerated overnight. The refrigerated filtrate is centrifuged with a centrifuge, rotated at 5000 revolutions per minute for 15 minutes, and filtered to obtain a mixed extract of honeysuckle, chrysanthemum indicum and mulberry leaves.

The invention discloses a method for extracting rhizoma acori graminei volatile oil by microwaves. The method comprises the following steps of: fetching a rhizoma acori graminei medical material; adding 8-10 weight times of distilled water, and soaking for 3-6 hours; putting in a microwave extractor; and extracting for 80-120min under the power of 600-800W to obtain the rhizoma acori graminei volatile oil. The technical scheme has the biggest characteristics that the extracting speed is high; the time is saved; the solvent consumption is low; and the effective component yield is high. Integrating the factors of all aspects, the technical scheme disclosed by the invention has the remarkable advantage of high extracting efficiency, and is very good in popularization and application prospect.

The invention discloses a method for extracting saponins from Dieffenbachia tiger's eye by using ultrasonic method combined with reverse micellar technology. The crude extract of saponins is extracted ultrasonically with 60-90% ethanol solution, evaporated to dryness and dissolved in water. And adjust the pH to 4.5-6.0, then extract with the reverse micelle system formed by isooctane and n-octanol mixed solvent and phosphate buffer, the obtained reverse micelle phase is mixed with phosphate buffer, and add ethyl acetate respectively , chloroform extraction, and evaporated to dryness. The method of the invention has the advantages of high selectivity, mild conditions, high yield and high purity.

The invention discloses a preparation method of folium mori nutritious protein instant powder. The preparation method comprises the following steps of 1) cleaning folium mori through running water, naturally drying in the shade, and crushing; 2) adding a 0.2 to 1.0% by mass NaCl aqueous solution to folium mori powder, ultrasonically processing at 200 to 500W for 10 to 40 minutes, digesting at 20 to 45 DEG C for 10 to 50 minutes, centrifuging, collecting centrifuged supernate, adjusting pH (Potential of Hydrogen) to 1 to 4.5 to realize acid precipitation, centrifuging, freezing and drying the obtained precipitate to obtain folium mori protein powder; 3) adding beta-cyclodextrin and neutral protein powder to the folium mori protein powder, adding water to dissolve; heating at 35 to 50 DEG C for 10 to 50 minutes, and filtering or centrifuging to obtain a folium mori nutritious protein powder solution; and 4) performing rotary distillation, concentrating and spray drying on the folium mori nutritious protein powder solution to obtain the folium mori nutritious protein instant powder.